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Properties of perimetric threshold estimates from Full Threshold, SITA Standard, and SITA Fast strategies.
Invest Ophthalmol Vis Sci. 2002 Aug; 43(8):2654-9.IO

Abstract

PURPOSE

To investigate the distributions of threshold estimates with the Swedish Interactive Threshold Algorithms (SITA) Standard, SITA Fast, and the Full Threshold algorithm (Humphrey Field Analyzer; Zeiss-Humphrey Instruments, Dublin, CA) and to compare the pointwise test-retest variability of these strategies.

METHODS

One eye of 49 patients (mean age, 61.6 years; range, 22-81) with glaucoma (Mean Deviation mean, -7.13 dB; range, +1.8 to -23.9 dB) was examined four times with each of the three strategies. The mean and median SITA Standard and SITA Fast threshold estimates were compared with a "best available" estimate of sensitivity (mean results of three Full Threshold tests). Pointwise 90% retest limits (5th and 95th percentiles of retest thresholds) were derived to assess the reproducibility of individual threshold estimates.

RESULTS

The differences between the threshold estimates of the SITA and Full Threshold strategies were largest (approximately 3 dB) for midrange sensitivities (approximately 15 dB). The threshold distributions of SITA were considerably different from those of the Full Threshold strategy. The differences remained of similar magnitude when the analysis was repeated on a subset of 20 locations that are examined early during the course of a Full Threshold examination. With sensitivities above 25 dB, both SITA strategies exhibited lower test-retest variability than the Full Threshold strategy. Below 25 dB, the retest intervals of SITA Standard were slightly smaller than those of the Full Threshold strategy, whereas those of SITA Fast were larger.

CONCLUSIONS

SITA Standard may be superior to the Full Threshold strategy for monitoring patients with visual field loss. The greater test-retest variability of SITA Fast in areas of low sensitivity is likely to offset the benefit of even shorter test durations with this strategy. The sensitivity differences between the SITA and Full Threshold strategies may relate to factors other than reduced fatigue. They are, however, small in comparison to the test-retest variability.

Authors+Show Affiliations

Department of Ophthalmology, Dalhousie University, Halifax, Nova Scotia, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12147599

Citation

Artes, Paul H., et al. "Properties of Perimetric Threshold Estimates From Full Threshold, SITA Standard, and SITA Fast Strategies." Investigative Ophthalmology & Visual Science, vol. 43, no. 8, 2002, pp. 2654-9.
Artes PH, Iwase A, Ohno Y, et al. Properties of perimetric threshold estimates from Full Threshold, SITA Standard, and SITA Fast strategies. Invest Ophthalmol Vis Sci. 2002;43(8):2654-9.
Artes, P. H., Iwase, A., Ohno, Y., Kitazawa, Y., & Chauhan, B. C. (2002). Properties of perimetric threshold estimates from Full Threshold, SITA Standard, and SITA Fast strategies. Investigative Ophthalmology & Visual Science, 43(8), 2654-9.
Artes PH, et al. Properties of Perimetric Threshold Estimates From Full Threshold, SITA Standard, and SITA Fast Strategies. Invest Ophthalmol Vis Sci. 2002;43(8):2654-9. PubMed PMID: 12147599.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Properties of perimetric threshold estimates from Full Threshold, SITA Standard, and SITA Fast strategies. AU - Artes,Paul H, AU - Iwase,Aiko, AU - Ohno,Yuko, AU - Kitazawa,Yoshiaki, AU - Chauhan,Balwantray C, PY - 2002/7/31/pubmed PY - 2002/8/8/medline PY - 2002/7/31/entrez SP - 2654 EP - 9 JF - Investigative ophthalmology & visual science JO - Invest Ophthalmol Vis Sci VL - 43 IS - 8 N2 - PURPOSE: To investigate the distributions of threshold estimates with the Swedish Interactive Threshold Algorithms (SITA) Standard, SITA Fast, and the Full Threshold algorithm (Humphrey Field Analyzer; Zeiss-Humphrey Instruments, Dublin, CA) and to compare the pointwise test-retest variability of these strategies. METHODS: One eye of 49 patients (mean age, 61.6 years; range, 22-81) with glaucoma (Mean Deviation mean, -7.13 dB; range, +1.8 to -23.9 dB) was examined four times with each of the three strategies. The mean and median SITA Standard and SITA Fast threshold estimates were compared with a "best available" estimate of sensitivity (mean results of three Full Threshold tests). Pointwise 90% retest limits (5th and 95th percentiles of retest thresholds) were derived to assess the reproducibility of individual threshold estimates. RESULTS: The differences between the threshold estimates of the SITA and Full Threshold strategies were largest (approximately 3 dB) for midrange sensitivities (approximately 15 dB). The threshold distributions of SITA were considerably different from those of the Full Threshold strategy. The differences remained of similar magnitude when the analysis was repeated on a subset of 20 locations that are examined early during the course of a Full Threshold examination. With sensitivities above 25 dB, both SITA strategies exhibited lower test-retest variability than the Full Threshold strategy. Below 25 dB, the retest intervals of SITA Standard were slightly smaller than those of the Full Threshold strategy, whereas those of SITA Fast were larger. CONCLUSIONS: SITA Standard may be superior to the Full Threshold strategy for monitoring patients with visual field loss. The greater test-retest variability of SITA Fast in areas of low sensitivity is likely to offset the benefit of even shorter test durations with this strategy. The sensitivity differences between the SITA and Full Threshold strategies may relate to factors other than reduced fatigue. They are, however, small in comparison to the test-retest variability. SN - 0146-0404 UR - https://www.unboundmedicine.com/medline/citation/12147599/Properties_of_perimetric_threshold_estimates_from_Full_Threshold_SITA_Standard_and_SITA_Fast_strategies_ L2 - https://iovs.arvojournals.org/article.aspx?volume=43&issue=8&page=2654 DB - PRIME DP - Unbound Medicine ER -