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[Subcutaneously implantable glucose sensors in patients with diabetes mellitus; still many problems].
Ned Tijdschr Geneeskd. 2002 Jul 13; 146(28):1313-6.NT

Abstract

Despite considerable scientific efforts, no clinical method is currently available for the continuous monitoring of glucose in subcutaneous tissue fluid. In general, good results were obtained during in-vitro experiments with various implantable glucose sensors. However, after implantation these devices exhibited a progressive loss of sensor function. It is evident that the tissue reaction to the implanted sensor, especially the interactions at the sensor-tissue interface, plays an important role in this loss of function. Adequate strategies to improve in-vivo sensor performance can only be developed if there is a better understanding of the processes involved in sensor inactivation.

Authors+Show Affiliations

Gerritsen M
Tweesteden Ziekenhuis, afd. Interne Geneeskunde, Postbus 90.107, 5000 LA Tilburg.
Jansen JA
No affiliation info available
Lutterman JA
No affiliation info available

MeSH

Biosensing TechniquesBlood GlucoseBlood Glucose Self-MonitoringDiabetes MellitusEquipment DesignEquipment FailureHumansMonitoring, PhysiologicProstheses and ImplantsSensitivity and Specificity

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

dut

PubMed ID

12148218

Citation

Gerritsen, M, et al. "[Subcutaneously Implantable Glucose Sensors in Patients With Diabetes Mellitus; Still Many Problems]." Nederlands Tijdschrift Voor Geneeskunde, vol. 146, no. 28, 2002, pp. 1313-6.
Gerritsen M, Jansen JA, Lutterman JA. [Subcutaneously implantable glucose sensors in patients with diabetes mellitus; still many problems]. Ned Tijdschr Geneeskd. 2002;146(28):1313-6.
Gerritsen, M., Jansen, J. A., & Lutterman, J. A. (2002). [Subcutaneously implantable glucose sensors in patients with diabetes mellitus; still many problems]. Nederlands Tijdschrift Voor Geneeskunde, 146(28), 1313-6.
Gerritsen M, Jansen JA, Lutterman JA. [Subcutaneously Implantable Glucose Sensors in Patients With Diabetes Mellitus; Still Many Problems]. Ned Tijdschr Geneeskd. 2002 Jul 13;146(28):1313-6. PubMed PMID: 12148218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Subcutaneously implantable glucose sensors in patients with diabetes mellitus; still many problems]. AU - Gerritsen,M, AU - Jansen,J A, AU - Lutterman,J A, PY - 2002/8/1/pubmed PY - 2002/10/17/medline PY - 2002/8/1/entrez SP - 1313 EP - 6 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 146 IS - 28 N2 - Despite considerable scientific efforts, no clinical method is currently available for the continuous monitoring of glucose in subcutaneous tissue fluid. In general, good results were obtained during in-vitro experiments with various implantable glucose sensors. However, after implantation these devices exhibited a progressive loss of sensor function. It is evident that the tissue reaction to the implanted sensor, especially the interactions at the sensor-tissue interface, plays an important role in this loss of function. Adequate strategies to improve in-vivo sensor performance can only be developed if there is a better understanding of the processes involved in sensor inactivation. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/12148218/[Subcutaneously_implantable_glucose_sensors_in_patients_with_diabetes_mellitus DB - PRIME DP - Unbound Medicine ER -