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Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra) in the treatment of erectile dysfunction in Brazilian and Mexican men.
Int J Impot Res. 2002 Aug; 14 Suppl 2:S27-32.IJ

Abstract

A 12-week, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of flexible-dose sildenafil citrate (Viagra) treatment (25, 50 or 100 mg) in Brazilian and Mexican men with erectile dysfunction (ED) of broad-spectrum etiology. Efficacy was assessed on the basis of responses to the 15-item International Index of Erectile Function (IIEF) questionnaire, completed at baseline and after 12 weeks of treatment. At end point, mean scores for all IIEF domains of sexual function (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) were significantly (P<0.0001) higher in the sildenafil group (n=109) than in the placebo group (n=105). These findings confirm the significant increases in frequency of penetration and frequency of maintained erections reported previously. Sildenafil treatment was well tolerated. The most common adverse events were headache and flushing. In conclusion, sildenafil is a well-tolerated and effective treatment for ED of broad-spectrum etiology in Latin American men.

Authors+Show Affiliations

Hospital Albert Einstein, São Paulo, Brazil. Glinas@originet.comb.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Randomized Controlled Trial

Language

eng

PubMed ID

12161765

Citation

Glina, S, et al. "Efficacy and Safety of Flexible-dose Oral Sildenafil Citrate (Viagra) in the Treatment of Erectile Dysfunction in Brazilian and Mexican Men." International Journal of Impotence Research, vol. 14 Suppl 2, 2002, pp. S27-32.
Glina S, Bertero E, Claro J, et al. Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra) in the treatment of erectile dysfunction in Brazilian and Mexican men. Int J Impot Res. 2002;14 Suppl 2:S27-32.
Glina, S., Bertero, E., Claro, J., Damião, R., Faria, G., Fregonesi, A., Jaspersen, J., Mendoza, A., Mattos, D., Rocha, L. C., Sotomayor, M., Telöken, C., Ureta, S., Zonana, E., & Ugarte, F. (2002). Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra) in the treatment of erectile dysfunction in Brazilian and Mexican men. International Journal of Impotence Research, 14 Suppl 2, S27-32.
Glina S, et al. Efficacy and Safety of Flexible-dose Oral Sildenafil Citrate (Viagra) in the Treatment of Erectile Dysfunction in Brazilian and Mexican Men. Int J Impot Res. 2002;14 Suppl 2:S27-32. PubMed PMID: 12161765.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra) in the treatment of erectile dysfunction in Brazilian and Mexican men. AU - Glina,S, AU - Bertero,E, AU - Claro,J, AU - Damião,R, AU - Faria,G, AU - Fregonesi,A, AU - Jaspersen,J, AU - Mendoza,A, AU - Mattos,D,Jr AU - Rocha,L C, AU - Sotomayor,M, AU - Telöken,C, AU - Ureta,S, AU - Zonana,E, AU - Ugarte,F, PY - 2002/8/6/pubmed PY - 2003/1/23/medline PY - 2002/8/6/entrez SP - S27 EP - 32 JF - International journal of impotence research JO - Int. J. Impot. Res. VL - 14 Suppl 2 N2 - A 12-week, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of flexible-dose sildenafil citrate (Viagra) treatment (25, 50 or 100 mg) in Brazilian and Mexican men with erectile dysfunction (ED) of broad-spectrum etiology. Efficacy was assessed on the basis of responses to the 15-item International Index of Erectile Function (IIEF) questionnaire, completed at baseline and after 12 weeks of treatment. At end point, mean scores for all IIEF domains of sexual function (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) were significantly (P<0.0001) higher in the sildenafil group (n=109) than in the placebo group (n=105). These findings confirm the significant increases in frequency of penetration and frequency of maintained erections reported previously. Sildenafil treatment was well tolerated. The most common adverse events were headache and flushing. In conclusion, sildenafil is a well-tolerated and effective treatment for ED of broad-spectrum etiology in Latin American men. SN - 0955-9930 UR - https://www.unboundmedicine.com/medline/citation/12161765/Efficacy_and_safety_of_flexible_dose_oral_sildenafil_citrate__Viagra__in_the_treatment_of_erectile_dysfunction_in_Brazilian_and_Mexican_men_ L2 - http://dx.doi.org/10.1038/sj.ijir.3900895 DB - PRIME DP - Unbound Medicine ER -