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Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population.

Abstract

The aim of this work was to study the relationship between excess body weight and the risks of hypertension and diabetes in the population of northeastern China. Subsections of a cross-sectional survey in Da Qing City were used to assess the relationship of excess weight to risk factors for coronary heart disease (CHD). A 6-year prospective study also assessed the probability of developing Type 2 diabetes. A total of 2856 adults (25-70 years of age) were assessed cross-sectionally and 629 non-diabetic subjects of similar age were followed-up for 6 years. Blood pressure, plasma fasting glucose, triglycerides, high-density lipoporotein (HDL) cholesterol and fibrinogen levels were measured as well as weight, height and waist and hip circumferences. About 45% of adults had a body mass index (BMI) of > or =25.0. Risk factors increased with increasing BMI from a baseline value of 21.0: at a BMI of 23.0-24.9, the risk of hypertension and hypertriglyceridaemia doubled; the risk increased threefold at a BMI of 25.0-26.9. The prevalence of Type 2 diabetes increased progressively in women within the normal BMI range and in men from a BMI of 25.0. Type 2 diabetes was four times as common if the BMI was >27.0. Increasing waist measurements predicted 10-fold increases in hypertension and a three-to-five times increased risk of diabetes. Suitable waist cut-off points were 85cm for men and 80cm for women, with statistical analysis showing waist as the more dominant predictor of risk than age, waist-to-hip ratios or BMIs. Hence, small increases in BMI, and particularly in waist circumference, predict a substantial increase in the risk of diabetes and risk for CHD, especially hypertension, in Chinese adults.

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  • Authors+Show Affiliations

    ,

    Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China. xiangyu@public.bta.net.cn

    , , , , ,

    Source

    MeSH

    Adult
    Aged
    Anthropometry
    Asian Continental Ancestry Group
    Blood Glucose
    Blood Pressure
    China
    Cholesterol, HDL
    Coronary Disease
    Cross-Sectional Studies
    Diabetes Mellitus, Type 2
    Female
    Fibrinogen
    Humans
    Hypertension
    Hypertriglyceridemia
    Male
    Middle Aged
    Obesity
    Prevalence
    Prospective Studies
    Risk Factors
    Sex Distribution
    Triglycerides

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    12164468

    Citation

    Li, G, et al. "Obesity, Coronary Heart Disease Risk Factors and Diabetes in Chinese: an Approach to the Criteria of Obesity in the Chinese Population." Obesity Reviews : an Official Journal of the International Association for the Study of Obesity, vol. 3, no. 3, 2002, pp. 167-72.
    Li G, Chen X, Jang Y, et al. Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population. Obes Rev. 2002;3(3):167-72.
    Li, G., Chen, X., Jang, Y., Wang, J., Xing, X., Yang, W., & Hu, Y. (2002). Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population. Obesity Reviews : an Official Journal of the International Association for the Study of Obesity, 3(3), pp. 167-72.
    Li G, et al. Obesity, Coronary Heart Disease Risk Factors and Diabetes in Chinese: an Approach to the Criteria of Obesity in the Chinese Population. Obes Rev. 2002;3(3):167-72. PubMed PMID: 12164468.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population. AU - Li,G, AU - Chen,X, AU - Jang,Y, AU - Wang,J, AU - Xing,X, AU - Yang,W, AU - Hu,Y, PY - 2002/8/8/pubmed PY - 2003/1/24/medline PY - 2002/8/8/entrez SP - 167 EP - 72 JF - Obesity reviews : an official journal of the International Association for the Study of Obesity JO - Obes Rev VL - 3 IS - 3 N2 - The aim of this work was to study the relationship between excess body weight and the risks of hypertension and diabetes in the population of northeastern China. Subsections of a cross-sectional survey in Da Qing City were used to assess the relationship of excess weight to risk factors for coronary heart disease (CHD). A 6-year prospective study also assessed the probability of developing Type 2 diabetes. A total of 2856 adults (25-70 years of age) were assessed cross-sectionally and 629 non-diabetic subjects of similar age were followed-up for 6 years. Blood pressure, plasma fasting glucose, triglycerides, high-density lipoporotein (HDL) cholesterol and fibrinogen levels were measured as well as weight, height and waist and hip circumferences. About 45% of adults had a body mass index (BMI) of > or =25.0. Risk factors increased with increasing BMI from a baseline value of 21.0: at a BMI of 23.0-24.9, the risk of hypertension and hypertriglyceridaemia doubled; the risk increased threefold at a BMI of 25.0-26.9. The prevalence of Type 2 diabetes increased progressively in women within the normal BMI range and in men from a BMI of 25.0. Type 2 diabetes was four times as common if the BMI was >27.0. Increasing waist measurements predicted 10-fold increases in hypertension and a three-to-five times increased risk of diabetes. Suitable waist cut-off points were 85cm for men and 80cm for women, with statistical analysis showing waist as the more dominant predictor of risk than age, waist-to-hip ratios or BMIs. Hence, small increases in BMI, and particularly in waist circumference, predict a substantial increase in the risk of diabetes and risk for CHD, especially hypertension, in Chinese adults. SN - 1467-7881 UR - https://www.unboundmedicine.com/medline/citation/12164468/Obesity_coronary_heart_disease_risk_factors_and_diabetes_in_Chinese:_an_approach_to_the_criteria_of_obesity_in_the_Chinese_population_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1467-7881&date=2002&volume=3&issue=3&spage=167 DB - PRIME DP - Unbound Medicine ER -