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Laryngeal collagen injection as an adjunct to medialization laryngoplasty.
Laryngoscope. 2002 Aug; 112(8 Pt 1):1407-13.L

Abstract

OBJECTIVES/HYPOTHESIS

Dysphonia associated with laryngeal paralysis may be identified in the short term postoperatively or may develop years after successful medialization laryngoplasty. In selected cases, laryngeal collagen injection permits further medialization of one or both vocal folds by small increments to improve phonation after medialization thyroplasty. The study seeks to determine whether collagen injections result in measurable improvements in voice quality and vocal function when offered to select patients who have received medialization thyroplasty.

STUDY DESIGN

Retrospective review of patient charts and voice database.

METHODS

Seven patients were treated with Zyderm II collagen using indirect mirror laryngoscopy and a curved injection apparatus. Changes in voice quality and function were assessed by comparing measures obtained before treatment (mean period, 5.6 d), shortly after treatment (mean period, 38.1 d), and in the long term after treatment (mean period, 226 d).

RESULTS

Mean self-ratings of the patient, clinician's ratings, and objective measures demonstrated measurable improvement in vocal function after collagen injection.

CONCLUSIONS

The office-based procedure offers a simple, efficient adjunct to open techniques of medialization laryngoplasty. Techniques of anesthesia, injection, and patient selection are discussed.

Authors+Show Affiliations

Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12172253

Citation

Hoffman, Henry, et al. "Laryngeal Collagen Injection as an Adjunct to Medialization Laryngoplasty." The Laryngoscope, vol. 112, no. 8 Pt 1, 2002, pp. 1407-13.
Hoffman H, McCabe D, McCulloch T, et al. Laryngeal collagen injection as an adjunct to medialization laryngoplasty. Laryngoscope. 2002;112(8 Pt 1):1407-13.
Hoffman, H., McCabe, D., McCulloch, T., Jin, S. M., & Karnell, M. (2002). Laryngeal collagen injection as an adjunct to medialization laryngoplasty. The Laryngoscope, 112(8 Pt 1), 1407-13.
Hoffman H, et al. Laryngeal Collagen Injection as an Adjunct to Medialization Laryngoplasty. Laryngoscope. 2002;112(8 Pt 1):1407-13. PubMed PMID: 12172253.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Laryngeal collagen injection as an adjunct to medialization laryngoplasty. AU - Hoffman,Henry, AU - McCabe,Daniel, AU - McCulloch,Timothy, AU - Jin,Sung M, AU - Karnell,Michael, PY - 2002/8/13/pubmed PY - 2002/9/28/medline PY - 2002/8/13/entrez SP - 1407 EP - 13 JF - The Laryngoscope JO - Laryngoscope VL - 112 IS - 8 Pt 1 N2 - OBJECTIVES/HYPOTHESIS: Dysphonia associated with laryngeal paralysis may be identified in the short term postoperatively or may develop years after successful medialization laryngoplasty. In selected cases, laryngeal collagen injection permits further medialization of one or both vocal folds by small increments to improve phonation after medialization thyroplasty. The study seeks to determine whether collagen injections result in measurable improvements in voice quality and vocal function when offered to select patients who have received medialization thyroplasty. STUDY DESIGN: Retrospective review of patient charts and voice database. METHODS: Seven patients were treated with Zyderm II collagen using indirect mirror laryngoscopy and a curved injection apparatus. Changes in voice quality and function were assessed by comparing measures obtained before treatment (mean period, 5.6 d), shortly after treatment (mean period, 38.1 d), and in the long term after treatment (mean period, 226 d). RESULTS: Mean self-ratings of the patient, clinician's ratings, and objective measures demonstrated measurable improvement in vocal function after collagen injection. CONCLUSIONS: The office-based procedure offers a simple, efficient adjunct to open techniques of medialization laryngoplasty. Techniques of anesthesia, injection, and patient selection are discussed. SN - 0023-852X UR - https://www.unboundmedicine.com/medline/citation/12172253/Laryngeal_collagen_injection_as_an_adjunct_to_medialization_laryngoplasty_ L2 - https://doi.org/10.1097/00005537-200208000-00015 DB - PRIME DP - Unbound Medicine ER -