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A research review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer.
Oncol Nurs Forum 2002; 29(7):1063-80ON

Abstract

PURPOSE/OBJECTIVES

To review the research studies on the current treatments for radiation therapy-(RT-) induced mucositis in patients with head and neck cancer.

DATA SOURCES

MEDLINE search of the literature from 1966-2001.

DATA SYNTHESIS

Four types of agents (i.e., antimicrobial, coating, anti-inflammatory, and cytokine-like agents) have been evaluated for the management of RT-induced oral mucositis in patients with head and neck cancer. Most of the published studies had relatively small sample sizes and used inconsistent measures to evaluate the extent and severity of oral mucositis. Therefore, definitive conclusions regarding the effectiveness of any of the agents tested in the prevention and treatment of RT-induced oral mucositis cannot be drawn.

CONCLUSIONS

Oral mucositis remains the most common complication among patients with head and neck cancer. Although a number of strategies and products are being investigated and new directions are promising, the therapies tested to date have not produced consistent results.

IMPLICATIONS FOR NURSING

The most effective measure to treat RT-induced mucositis in patients with head and neck cancer is frequent oral rinsing with a bland mouthwash, such as saline or a sodium bicarbonate rinse, to reduce the amount of oral microbial flora. Dental care, consistent oral assessments, and the initiation of a standardized oral hygiene protocol before the initiation of cancer treatment are the most effective approaches for oral mucositis.

Authors+Show Affiliations

School of Nursing, University of California, San Francisco, CA, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12183755

Citation

Shih, Aishan, et al. "A Research Review of the Current Treatments for Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer." Oncology Nursing Forum, vol. 29, no. 7, 2002, pp. 1063-80.
Shih A, Miaskowski C, Dodd MJ, et al. A research review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer. Oncol Nurs Forum. 2002;29(7):1063-80.
Shih, A., Miaskowski, C., Dodd, M. J., Stotts, N. A., & MacPhail, L. (2002). A research review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer. Oncology Nursing Forum, 29(7), pp. 1063-80.
Shih A, et al. A Research Review of the Current Treatments for Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer. Oncol Nurs Forum. 2002;29(7):1063-80. PubMed PMID: 12183755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A research review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer. AU - Shih,Aishan, AU - Miaskowski,Christine, AU - Dodd,Marilyn J, AU - Stotts,Nancy A, AU - MacPhail,Laurie, PY - 2002/8/17/pubmed PY - 2002/10/29/medline PY - 2002/8/17/entrez SP - 1063 EP - 80 JF - Oncology nursing forum JO - Oncol Nurs Forum VL - 29 IS - 7 N2 - PURPOSE/OBJECTIVES: To review the research studies on the current treatments for radiation therapy-(RT-) induced mucositis in patients with head and neck cancer. DATA SOURCES: MEDLINE search of the literature from 1966-2001. DATA SYNTHESIS: Four types of agents (i.e., antimicrobial, coating, anti-inflammatory, and cytokine-like agents) have been evaluated for the management of RT-induced oral mucositis in patients with head and neck cancer. Most of the published studies had relatively small sample sizes and used inconsistent measures to evaluate the extent and severity of oral mucositis. Therefore, definitive conclusions regarding the effectiveness of any of the agents tested in the prevention and treatment of RT-induced oral mucositis cannot be drawn. CONCLUSIONS: Oral mucositis remains the most common complication among patients with head and neck cancer. Although a number of strategies and products are being investigated and new directions are promising, the therapies tested to date have not produced consistent results. IMPLICATIONS FOR NURSING: The most effective measure to treat RT-induced mucositis in patients with head and neck cancer is frequent oral rinsing with a bland mouthwash, such as saline or a sodium bicarbonate rinse, to reduce the amount of oral microbial flora. Dental care, consistent oral assessments, and the initiation of a standardized oral hygiene protocol before the initiation of cancer treatment are the most effective approaches for oral mucositis. SN - 1538-0688 UR - https://www.unboundmedicine.com/medline/citation/12183755/A_research_review_of_the_current_treatments_for_radiation_induced_oral_mucositis_in_patients_with_head_and_neck_cancer_ L2 - http://store.ons.org/article/find?doi=10.1188/02.ONF.1063-1080 DB - PRIME DP - Unbound Medicine ER -