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Which is the best distension protocol to study rectal sensitivity in the irritable bowel syndrome?
Rev Esp Enferm Dig. 2002 Apr; 94(4):211-20.RE

Abstract

OBJECTIVE

To evaluate any differences in rectal distension perception between healthy subjects and patients with irritable bowel syndrome (IBS) according to an isobaric distension protocol (progressive or phasic).

MATERIAL AND METHODS

10 healthy subjects and 41 patients with IBS (Rome II criteria). Rectal distension was performed using a barostat connected to a 500 mL bag, and a progressive distension protocol (continuous distension at a rate of 0.36 mmHg/sec) was compared to phasic distension protocol (distensions for 60 sec with 4 mmHg increases separated by 0 mmHg pressures during 60 sec). Perception was evaluated using three descriptive scales of 7 categories each for perception type, intensity, and affectivity. Perception thresholds were assessed.

RESULTS

No significant differences in any perception thresholds were found between control subjects and IBS patients using a progressive distension protocol. Differences in the perception of inconvenient distension and maximum tolerable distension were encountered with the phasic distension protocol. Uncomfortable distension thresholds below those of controls were found in 48.8% of patients with IBS when a phasic distension protocol was used, versus only 9.7% with a progressive protocol.

CONCLUSION

Hypersensitivity in patients with IBS is mainly seen with the use of phasic distension isobaric protocols for affective negative perceptions.

Authors+Show Affiliations

Department of Gastroenterology, Hospital Clínico San Carlos, C/Martín Lagos s/n. 28040 Madrid. Spain. enrique.rey@erey.netNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng spa

PubMed ID

12185932

Citation

Rey, E, et al. "Which Is the Best Distension Protocol to Study Rectal Sensitivity in the Irritable Bowel Syndrome?" Revista Espanola De Enfermedades Digestivas : Organo Oficial De La Sociedad Espanola De Patologia Digestiva, vol. 94, no. 4, 2002, pp. 211-20.
Rey E, Alvarez Sánchez A, Díaz-Rubio M. Which is the best distension protocol to study rectal sensitivity in the irritable bowel syndrome? Rev Esp Enferm Dig. 2002;94(4):211-20.
Rey, E., Alvarez Sánchez, A., & Díaz-Rubio, M. (2002). Which is the best distension protocol to study rectal sensitivity in the irritable bowel syndrome? Revista Espanola De Enfermedades Digestivas : Organo Oficial De La Sociedad Espanola De Patologia Digestiva, 94(4), 211-20.
Rey E, Alvarez Sánchez A, Díaz-Rubio M. Which Is the Best Distension Protocol to Study Rectal Sensitivity in the Irritable Bowel Syndrome. Rev Esp Enferm Dig. 2002;94(4):211-20. PubMed PMID: 12185932.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Which is the best distension protocol to study rectal sensitivity in the irritable bowel syndrome? AU - Rey,E, AU - Alvarez Sánchez,A, AU - Díaz-Rubio,M, PY - 2002/8/21/pubmed PY - 2002/9/21/medline PY - 2002/8/21/entrez SP - 211 EP - 20 JF - Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva JO - Rev Esp Enferm Dig VL - 94 IS - 4 N2 - OBJECTIVE: To evaluate any differences in rectal distension perception between healthy subjects and patients with irritable bowel syndrome (IBS) according to an isobaric distension protocol (progressive or phasic). MATERIAL AND METHODS: 10 healthy subjects and 41 patients with IBS (Rome II criteria). Rectal distension was performed using a barostat connected to a 500 mL bag, and a progressive distension protocol (continuous distension at a rate of 0.36 mmHg/sec) was compared to phasic distension protocol (distensions for 60 sec with 4 mmHg increases separated by 0 mmHg pressures during 60 sec). Perception was evaluated using three descriptive scales of 7 categories each for perception type, intensity, and affectivity. Perception thresholds were assessed. RESULTS: No significant differences in any perception thresholds were found between control subjects and IBS patients using a progressive distension protocol. Differences in the perception of inconvenient distension and maximum tolerable distension were encountered with the phasic distension protocol. Uncomfortable distension thresholds below those of controls were found in 48.8% of patients with IBS when a phasic distension protocol was used, versus only 9.7% with a progressive protocol. CONCLUSION: Hypersensitivity in patients with IBS is mainly seen with the use of phasic distension isobaric protocols for affective negative perceptions. SN - 1130-0108 UR - https://www.unboundmedicine.com/medline/citation/12185932/Which_is_the_best_distension_protocol_to_study_rectal_sensitivity_in_the_irritable_bowel_syndrome L2 - http://www.diseaseinfosearch.org/result/3876 DB - PRIME DP - Unbound Medicine ER -