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Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study.
Int J Geriatr Psychiatry. 2002 Aug; 17(8):699-703.IJ

Abstract

OBJECTIVES

the purpose of this preliminary study was to determine if clock drawing performance may help to differentiate between dementia of the Alzheimer's type (DAT) and vascular dementia (VD) patients.

METHODS

eighty-eight community-dwelling outpatients were comprehensively evaluated and met DSM-IV criteria for DAT or VD. Cognitive evaluation included the Mini-Mental State Examination (MMSE) and the Cambridge Cognitive Examination (CAMCOG). CAMCOG derived clock drawings were blindly evaluated by the same investigator, according to Freedman's method for clock drawing, and a total score as well as subscores (contour, numbers, hands and center) were determined.

RESULTS

There were no significant differences between DAT and VD patients in terms of demographic (age, gender, education) and cognitive (MMSE score, CAMCOG score) characteristics. On the average, the VD group showed slightly poorer performance on each of the clock drawing test (CDT) measures studied. With application of the Bonferroni correction, only Freedman's total score and hands subscore were statistically different between groups (p<0.003, p<0.004, respectively). Stepwise logistic regression analyses showed that the only significant variable was Freedman's total score (B=-0.273, p=0.005). Stepwise discriminant analysis identified Freedman's total score as the only significant predictor of diagnosis (Wilkes' lambda=0.903, p=0.003). This model correctly classified 65.9% overall into the respective DAT and VD groups.

CONCLUSIONS

CDT scored according to a comprehensive technique may be of value in differentiating DAT from VD patients. We hypothesize that the classificatory ability of Freedman's method might be attributed to its presumed sensitivity to impaired executive functioning which is more pronounced in VD compared with DAT patients.

Authors+Show Affiliations

Margoletz Psychogeriatric Center, Ichilov Hospital, Tel-Aviv, Israel. heinik@post.tau.ac.ilNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12211117

Citation

Heinik, Jeremia, et al. "Can Clock Drawing Test Help to Differentiate Between Dementia of the Alzheimer's Type and Vascular Dementia? a Preliminary Study." International Journal of Geriatric Psychiatry, vol. 17, no. 8, 2002, pp. 699-703.
Heinik J, Solomesh I, Raikher B, et al. Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study. Int J Geriatr Psychiatry. 2002;17(8):699-703.
Heinik, J., Solomesh, I., Raikher, B., & Lin, R. (2002). Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study. International Journal of Geriatric Psychiatry, 17(8), 699-703.
Heinik J, et al. Can Clock Drawing Test Help to Differentiate Between Dementia of the Alzheimer's Type and Vascular Dementia? a Preliminary Study. Int J Geriatr Psychiatry. 2002;17(8):699-703. PubMed PMID: 12211117.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study. AU - Heinik,Jeremia, AU - Solomesh,Isaac, AU - Raikher,Boris, AU - Lin,Ruth, PY - 2002/9/5/pubmed PY - 2002/10/17/medline PY - 2002/9/5/entrez SP - 699 EP - 703 JF - International journal of geriatric psychiatry JO - Int J Geriatr Psychiatry VL - 17 IS - 8 N2 - OBJECTIVES: the purpose of this preliminary study was to determine if clock drawing performance may help to differentiate between dementia of the Alzheimer's type (DAT) and vascular dementia (VD) patients. METHODS: eighty-eight community-dwelling outpatients were comprehensively evaluated and met DSM-IV criteria for DAT or VD. Cognitive evaluation included the Mini-Mental State Examination (MMSE) and the Cambridge Cognitive Examination (CAMCOG). CAMCOG derived clock drawings were blindly evaluated by the same investigator, according to Freedman's method for clock drawing, and a total score as well as subscores (contour, numbers, hands and center) were determined. RESULTS: There were no significant differences between DAT and VD patients in terms of demographic (age, gender, education) and cognitive (MMSE score, CAMCOG score) characteristics. On the average, the VD group showed slightly poorer performance on each of the clock drawing test (CDT) measures studied. With application of the Bonferroni correction, only Freedman's total score and hands subscore were statistically different between groups (p<0.003, p<0.004, respectively). Stepwise logistic regression analyses showed that the only significant variable was Freedman's total score (B=-0.273, p=0.005). Stepwise discriminant analysis identified Freedman's total score as the only significant predictor of diagnosis (Wilkes' lambda=0.903, p=0.003). This model correctly classified 65.9% overall into the respective DAT and VD groups. CONCLUSIONS: CDT scored according to a comprehensive technique may be of value in differentiating DAT from VD patients. We hypothesize that the classificatory ability of Freedman's method might be attributed to its presumed sensitivity to impaired executive functioning which is more pronounced in VD compared with DAT patients. SN - 0885-6230 UR - https://www.unboundmedicine.com/medline/citation/12211117/Can_clock_drawing_test_help_to_differentiate_between_dementia_of_the_Alzheimer's_type_and_vascular_dementia_A_preliminary_study_ L2 - https://doi.org/10.1002/gps.678 DB - PRIME DP - Unbound Medicine ER -