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[Expression of bcl-2 in the normal endometrium and endometrium of adenomyosis].
Hunan Yi Ke Da Xue Xue Bao. 2000 Oct 28; 25(5):453-6.HY

Abstract

Using immunohistochemical ABC staining, we detected the expression and role of bcl-2 in normal endometrium(n = 17) and eutopic and ectopic endometrium with adenomyosis(n = 16) during the menstrual cycle. The first result was that the expressions of bcl-2 in the eutopic endometrium were the same as the normal endometrium, showing predominantly in the glandular epithelial cells, and obviously cyclic changes throughout the menstrual cycle. This result suggests that these changes may be regulated by ovarian hormone and play an important role in the proliferation and physiologic death of normal endometrial glandular epithelial cells to regulate the menstrual cycle. Bcl-2 expression in the glandular cells of ectopic endometrium of adenomyosis had no cyclic change and bcl-2 staining had remained in the whole menstrual cycle. The second result suggests that the above mentioned phenomena may play an important role in the pathogenesis of adenomyosis.

Authors+Show Affiliations

Department of Gynecology and Obstetrics, The Second Affiliated Hospital, Hunan Medical University, Changsha 410011.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

12212116

Citation

Huang, F, et al. "[Expression of Bcl-2 in the Normal Endometrium and Endometrium of Adenomyosis]." Hunan Yi Ke Da Xue Xue Bao = Hunan Yike Daxue Xuebao = Bulletin of Hunan Medical University, vol. 25, no. 5, 2000, pp. 453-6.
Huang F, Lin QH, Liu FY, et al. [Expression of bcl-2 in the normal endometrium and endometrium of adenomyosis]. Hunan Yi Ke Da Xue Xue Bao. 2000;25(5):453-6.
Huang, F., Lin, Q. H., Liu, F. Y., & Zhong, Z. S. (2000). [Expression of bcl-2 in the normal endometrium and endometrium of adenomyosis]. Hunan Yi Ke Da Xue Xue Bao = Hunan Yike Daxue Xuebao = Bulletin of Hunan Medical University, 25(5), 453-6.
Huang F, et al. [Expression of Bcl-2 in the Normal Endometrium and Endometrium of Adenomyosis]. Hunan Yi Ke Da Xue Xue Bao. 2000 Oct 28;25(5):453-6. PubMed PMID: 12212116.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Expression of bcl-2 in the normal endometrium and endometrium of adenomyosis]. AU - Huang,F, AU - Lin,Q H, AU - Liu,F Y, AU - Zhong,Z S, PY - 2002/9/6/pubmed PY - 2003/2/26/medline PY - 2002/9/6/entrez SP - 453 EP - 6 JF - Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University JO - Hunan Yi Ke Da Xue Xue Bao VL - 25 IS - 5 N2 - Using immunohistochemical ABC staining, we detected the expression and role of bcl-2 in normal endometrium(n = 17) and eutopic and ectopic endometrium with adenomyosis(n = 16) during the menstrual cycle. The first result was that the expressions of bcl-2 in the eutopic endometrium were the same as the normal endometrium, showing predominantly in the glandular epithelial cells, and obviously cyclic changes throughout the menstrual cycle. This result suggests that these changes may be regulated by ovarian hormone and play an important role in the proliferation and physiologic death of normal endometrial glandular epithelial cells to regulate the menstrual cycle. Bcl-2 expression in the glandular cells of ectopic endometrium of adenomyosis had no cyclic change and bcl-2 staining had remained in the whole menstrual cycle. The second result suggests that the above mentioned phenomena may play an important role in the pathogenesis of adenomyosis. SN - 1000-5625 UR - https://www.unboundmedicine.com/medline/citation/12212116/[Expression_of_bcl_2_in_the_normal_endometrium_and_endometrium_of_adenomyosis]_ L2 - http://www.diseaseinfosearch.org/result/226 DB - PRIME DP - Unbound Medicine ER -
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