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Advances in polycystic ovary syndrome treatment: metformin and ovarian diathermy.
Curr Womens Health Rep. 2002 Oct; 2(5):333-7.CW

Abstract

Polycystic ovary syndrome (PCOS) affects approximately 6% of women in their reproductive years. The symptoms of the syndrome are chronic anovulation and androgen excess. Infertility due to ovulatory dysfunction is a common problem for women with PCOS. Metformin, an antihyperglycemic agent, can correct the metabolic dysfunction that occurs with PCOS, and also stimulate folliculogenesis. The drug is effective alone and in combination with clomiphene citrate. An alternative option, ovarian diathermy, also promotes ovulation through changes in the intraovarian hormonal environment. Both techniques provide promising and effective alternatives for women with PCOS who do not respond to traditional oral ovulation induction agents.

Authors+Show Affiliations

Leclair C
Department of Obstetrics & Gynecology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201-3098, USA. leclairc@ohsu.edu
Patton PE
No affiliation info available

MeSH

AlgorithmsAnovulationClomipheneCombined Modality TherapyDiathermyFemaleHumansHyperinsulinismHypoglycemic AgentsMetforminOvarian FollicleOvulation InductionPolycystic Ovary Syndrome

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12215305

Citation

Leclair, Catherine, and Phillip E. Patton. "Advances in Polycystic Ovary Syndrome Treatment: Metformin and Ovarian Diathermy." Current Women's Health Reports, vol. 2, no. 5, 2002, pp. 333-7.
Leclair C, Patton PE. Advances in polycystic ovary syndrome treatment: metformin and ovarian diathermy. Curr Womens Health Rep. 2002;2(5):333-7.
Leclair, C., & Patton, P. E. (2002). Advances in polycystic ovary syndrome treatment: metformin and ovarian diathermy. Current Women's Health Reports, 2(5), 333-7.
Leclair C, Patton PE. Advances in Polycystic Ovary Syndrome Treatment: Metformin and Ovarian Diathermy. Curr Womens Health Rep. 2002;2(5):333-7. PubMed PMID: 12215305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Advances in polycystic ovary syndrome treatment: metformin and ovarian diathermy. AU - Leclair,Catherine, AU - Patton,Phillip E, PY - 2002/9/7/pubmed PY - 2002/11/26/medline PY - 2002/9/7/entrez SP - 333 EP - 7 JF - Current women's health reports JO - Curr Womens Health Rep VL - 2 IS - 5 N2 - Polycystic ovary syndrome (PCOS) affects approximately 6% of women in their reproductive years. The symptoms of the syndrome are chronic anovulation and androgen excess. Infertility due to ovulatory dysfunction is a common problem for women with PCOS. Metformin, an antihyperglycemic agent, can correct the metabolic dysfunction that occurs with PCOS, and also stimulate folliculogenesis. The drug is effective alone and in combination with clomiphene citrate. An alternative option, ovarian diathermy, also promotes ovulation through changes in the intraovarian hormonal environment. Both techniques provide promising and effective alternatives for women with PCOS who do not respond to traditional oral ovulation induction agents. SN - 1534-5874 UR - https://www.unboundmedicine.com/medline/citation/12215305/Advances_in_polycystic_ovary_syndrome_treatment:_metformin_and_ovarian_diathermy_ DB - PRIME DP - Unbound Medicine ER -