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Systemic antibiotic therapy for acne: a review.
Skin Therapy Lett. 2002 May; 7(5):3-7.ST

Abstract

Acne is a multifactorial disease of the pilosebaceous unit in the skin. Four contributing pathogenic factors need to be elucidated and include excess sebum production, follicular hyperkeratinization, colonization of the pilosebaceous unit by Propionibacterium acnes, which is a gram positive anaerobic diphtheroid, and the release of inflammatory mediators into the follicle and dermis. One or more of these factors are targeted by each of the systemic therapies for this disease and its variant, including systemic antibiotic therapies, which will be reviewed here.

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Authors+Show Affiliations

Kunynetz R
Division of Dermatology, Department of Medicine, University of Toronto, Ontario, Canada.

MeSH

Acne VulgarisAnti-Bacterial AgentsAnti-Infective AgentsDrug Resistance, BacterialHumansTrimethoprim, Sulfamethoxazole Drug Combination

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12223979

Citation

Kunynetz, R. "Systemic Antibiotic Therapy for Acne: a Review." Skin Therapy Letter, vol. 7, no. 5, 2002, pp. 3-7.
Kunynetz R. Systemic antibiotic therapy for acne: a review. Skin Therapy Lett. 2002;7(5):3-7.
Kunynetz, R. (2002). Systemic antibiotic therapy for acne: a review. Skin Therapy Letter, 7(5), 3-7.
Kunynetz R. Systemic Antibiotic Therapy for Acne: a Review. Skin Therapy Lett. 2002;7(5):3-7. PubMed PMID: 12223979.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Systemic antibiotic therapy for acne: a review. A1 - Kunynetz,R, PY - 2002/9/12/pubmed PY - 2002/10/31/medline PY - 2002/9/12/entrez SP - 3 EP - 7 JF - Skin therapy letter JO - Skin Therapy Lett VL - 7 IS - 5 N2 - Acne is a multifactorial disease of the pilosebaceous unit in the skin. Four contributing pathogenic factors need to be elucidated and include excess sebum production, follicular hyperkeratinization, colonization of the pilosebaceous unit by Propionibacterium acnes, which is a gram positive anaerobic diphtheroid, and the release of inflammatory mediators into the follicle and dermis. One or more of these factors are targeted by each of the systemic therapies for this disease and its variant, including systemic antibiotic therapies, which will be reviewed here. SN - 1201-5989 UR - https://www.unboundmedicine.com/medline/citation/12223979/Systemic_antibiotic_therapy_for_acne:_a_review_ L2 - https://medlineplus.gov/acne.html DB - PRIME DP - Unbound Medicine ER -