Tags

Type your tag names separated by a space and hit enter

Calcipotriol cream in the morning and ointment in the evening: a novel regimen to improve compliance.
J Dermatolog Treat. 2001 Jun; 12(2):75-9.JD

Abstract

BACKGROUND

Calcipotriol ointment and calcipotriol cream have both been shown to be effective in the treatment of psoriasis.

AIM

To find out the patient compliance, efficacy and tolerance to a regimen of a calcipotriol cream application in the morning and a calcipotriol ointment application in the evening.

METHODS

In order to obtain data relevant to daily practice, information was obtained from patients and dermatologists on the treatment of psoriasis with a combination of calcipotriol ointment and calcipotriol cream. In total, three assessments were carried out: at the beginning, after 3 weeks and after 8 weeks. The first assessment comprised general demographics, localization of the lesions, the percentage body surface involved, and details on other antipsoriatic medications. The second and third assessments were an evaluation of compliance and efficacy in comparison with calcipotriol ointment monotherapy, provided that the patients had experience with this treatment. In total, 976 patients were included by 170 dermatologists in The Netherlands and Belgium.

RESULTS

Compliance with the combined use of calcipotriol cream in the morning and calcipotriol ointment in the evening was optimal in 60-70% of the patients. The highest compliance was shown at the second visit but dropped at the third visit. Those patients with previous experience of calcipotriol ointment indicated that the calcipotriol cream/ointment regimen was a better principle. Response to the calcipotriol cream/ointment regimen was considered good in 67-76% of the patients.

CONCLUSION

The present study indicates that the combined use of calcipotriol cream in the morning and ointment in the evening is useful as a principle for mild to severe psoriasis. A total of 67-68% of the patients stated that this regimen was the most preferred topical treatment of psoriasis.

Authors+Show Affiliations

Department of Dermatology, University Hospital Nijmegen, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12243662

Citation

van de Kerkhof, P C., et al. "Calcipotriol Cream in the Morning and Ointment in the Evening: a Novel Regimen to Improve Compliance." The Journal of Dermatological Treatment, vol. 12, no. 2, 2001, pp. 75-9.
van de Kerkhof PC, Franssen M, de La Brassine M, et al. Calcipotriol cream in the morning and ointment in the evening: a novel regimen to improve compliance. J Dermatolog Treat. 2001;12(2):75-9.
van de Kerkhof, P. C., Franssen, M., de La Brassine, M., & Kuipers, M. (2001). Calcipotriol cream in the morning and ointment in the evening: a novel regimen to improve compliance. The Journal of Dermatological Treatment, 12(2), 75-9.
van de Kerkhof PC, et al. Calcipotriol Cream in the Morning and Ointment in the Evening: a Novel Regimen to Improve Compliance. J Dermatolog Treat. 2001;12(2):75-9. PubMed PMID: 12243662.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Calcipotriol cream in the morning and ointment in the evening: a novel regimen to improve compliance. AU - van de Kerkhof,P C, AU - Franssen,M, AU - de La Brassine,M, AU - Kuipers,M, PY - 2002/9/24/pubmed PY - 2002/10/9/medline PY - 2002/9/24/entrez SP - 75 EP - 9 JF - The Journal of dermatological treatment JO - J Dermatolog Treat VL - 12 IS - 2 N2 - BACKGROUND: Calcipotriol ointment and calcipotriol cream have both been shown to be effective in the treatment of psoriasis. AIM: To find out the patient compliance, efficacy and tolerance to a regimen of a calcipotriol cream application in the morning and a calcipotriol ointment application in the evening. METHODS: In order to obtain data relevant to daily practice, information was obtained from patients and dermatologists on the treatment of psoriasis with a combination of calcipotriol ointment and calcipotriol cream. In total, three assessments were carried out: at the beginning, after 3 weeks and after 8 weeks. The first assessment comprised general demographics, localization of the lesions, the percentage body surface involved, and details on other antipsoriatic medications. The second and third assessments were an evaluation of compliance and efficacy in comparison with calcipotriol ointment monotherapy, provided that the patients had experience with this treatment. In total, 976 patients were included by 170 dermatologists in The Netherlands and Belgium. RESULTS: Compliance with the combined use of calcipotriol cream in the morning and calcipotriol ointment in the evening was optimal in 60-70% of the patients. The highest compliance was shown at the second visit but dropped at the third visit. Those patients with previous experience of calcipotriol ointment indicated that the calcipotriol cream/ointment regimen was a better principle. Response to the calcipotriol cream/ointment regimen was considered good in 67-76% of the patients. CONCLUSION: The present study indicates that the combined use of calcipotriol cream in the morning and ointment in the evening is useful as a principle for mild to severe psoriasis. A total of 67-68% of the patients stated that this regimen was the most preferred topical treatment of psoriasis. SN - 0954-6634 UR - https://www.unboundmedicine.com/medline/citation/12243662/Calcipotriol_cream_in_the_morning_and_ointment_in_the_evening:_a_novel_regimen_to_improve_compliance_ L2 - https://www.tandfonline.com/doi/full/10.1080/095466301317085345 DB - PRIME DP - Unbound Medicine ER -