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Treatment of multiple miliary osteoma cutis of the face with local application of tretinoin (all-trans-retinoic acid): a case report and review of the literature.

Abstract

BACKGROUND

Multiple miliary osteoma cutis of the face represents primary extra-skeletal bone formation that arises within the skin of the face.

METHODS

A 60-year-old woman with multiple miliary osteoma cutis of the face was treated by application of 0.05% tretinoin (all-trans-retinoic acid) cream nightly.

RESULTS

After 3 months of therapy there were fewer papules and a decrease in size of remaining lesions. In a literature search, it was found that local application of tretinoin was successful and achieved a decrease in the number of papules over the face in all patients with multiple miliary osteoma cutis of the face; however, the length of time to achieve response varied from a few weeks to 6 months.

CONCLUSION

It is suggested that local application of tretinoin cream should be considered in the therapy of multiple miliary osteoma cutis of the face, particularly when the lesions are small and superficial.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Dermatology Institute Clalit Health Services, Beer-Sheva, Israel. arcohen@bgumail.bgu.ac.il

    , , ,

    Source

    MeSH

    Administration, Topical
    Facial Dermatoses
    Female
    Humans
    Keratolytic Agents
    Middle Aged
    Ossification, Heterotopic
    Skin Diseases
    Tretinoin

    Pub Type(s)

    Case Reports
    Journal Article
    Review

    Language

    eng

    PubMed ID

    12243710

    Citation

    Cohen, A D., et al. "Treatment of Multiple Miliary Osteoma Cutis of the Face With Local Application of Tretinoin (all-trans-retinoic Acid): a Case Report and Review of the Literature." The Journal of Dermatological Treatment, vol. 12, no. 3, 2001, pp. 171-3.
    Cohen AD, Chetov T, Cagnano E, et al. Treatment of multiple miliary osteoma cutis of the face with local application of tretinoin (all-trans-retinoic acid): a case report and review of the literature. J Dermatolog Treat. 2001;12(3):171-3.
    Cohen, A. D., Chetov, T., Cagnano, E., Naimer, S., & Vardy, D. A. (2001). Treatment of multiple miliary osteoma cutis of the face with local application of tretinoin (all-trans-retinoic acid): a case report and review of the literature. The Journal of Dermatological Treatment, 12(3), pp. 171-3.
    Cohen AD, et al. Treatment of Multiple Miliary Osteoma Cutis of the Face With Local Application of Tretinoin (all-trans-retinoic Acid): a Case Report and Review of the Literature. J Dermatolog Treat. 2001;12(3):171-3. PubMed PMID: 12243710.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Treatment of multiple miliary osteoma cutis of the face with local application of tretinoin (all-trans-retinoic acid): a case report and review of the literature. AU - Cohen,A D, AU - Chetov,T, AU - Cagnano,E, AU - Naimer,S, AU - Vardy,D A, PY - 2002/9/24/pubmed PY - 2002/10/9/medline PY - 2002/9/24/entrez SP - 171 EP - 3 JF - The Journal of dermatological treatment JO - J Dermatolog Treat VL - 12 IS - 3 N2 - BACKGROUND: Multiple miliary osteoma cutis of the face represents primary extra-skeletal bone formation that arises within the skin of the face. METHODS: A 60-year-old woman with multiple miliary osteoma cutis of the face was treated by application of 0.05% tretinoin (all-trans-retinoic acid) cream nightly. RESULTS: After 3 months of therapy there were fewer papules and a decrease in size of remaining lesions. In a literature search, it was found that local application of tretinoin was successful and achieved a decrease in the number of papules over the face in all patients with multiple miliary osteoma cutis of the face; however, the length of time to achieve response varied from a few weeks to 6 months. CONCLUSION: It is suggested that local application of tretinoin cream should be considered in the therapy of multiple miliary osteoma cutis of the face, particularly when the lesions are small and superficial. SN - 0954-6634 UR - https://www.unboundmedicine.com/medline/citation/12243710/Treatment_of_multiple_miliary_osteoma_cutis_of_the_face_with_local_application_of_tretinoin__all_trans_retinoic_acid_:_a_case_report_and_review_of_the_literature_ L2 - http://www.tandfonline.com/doi/full/10.1080/09546630152607925 DB - PRIME DP - Unbound Medicine ER -