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Role of magnetic resonance imaging in the diagnosis and single-stage surgical resection of invasive lobular carcinoma of the breast.
Br J Surg. 2002 Oct; 89(10):1296-301.BJ

Abstract

BACKGROUND

Conventional imaging with mammography and ultrasonography has a low sensitivity for diagnosis and a tendency to underestimate the extent of invasive lobular carcinoma (ILC) of the breast. The aim was to determine whether magnetic resonance imaging (MRI) had any advantages for the characterization of ILC.

METHODS

Twenty patients with histologically proven ILC underwent preoperative imaging with MRI. MRI was performed to aid detection of malignancy in six patients with a clinically suspicious presentation but normal or indeterminate imaging on mammography and ultrasonography. In 14 patients MRI was performed to determine tumour extent.

RESULTS

MRI accurately identified malignancy in five of six patients with normal or indeterminate conventional imaging. In seven of 14 patients in whom MRI was performed to determine tumour extent, it provided significant additional information. These included four patients in whom conventional imaging grossly underestimated tumour size, two patients in whom MRI identified an unsuspected contralateral breast tumour and one patient in whom MRI predicted tumour invasion of the pectoral muscle. The correlation between tumour size on histological examination was better with MRI (r = 0.967) than with mammography (r = 0.663) and ultrasonography (r = 0.673).

CONCLUSION

MRI can provide considerable additional information in the detection and characterization of ILC.

Authors+Show Affiliations

Department of Surgery, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12296901

Citation

Munot, K, et al. "Role of Magnetic Resonance Imaging in the Diagnosis and Single-stage Surgical Resection of Invasive Lobular Carcinoma of the Breast." The British Journal of Surgery, vol. 89, no. 10, 2002, pp. 1296-301.
Munot K, Dall B, Achuthan R, et al. Role of magnetic resonance imaging in the diagnosis and single-stage surgical resection of invasive lobular carcinoma of the breast. Br J Surg. 2002;89(10):1296-301.
Munot, K., Dall, B., Achuthan, R., Parkin, G., Lane, S., & Horgan, K. (2002). Role of magnetic resonance imaging in the diagnosis and single-stage surgical resection of invasive lobular carcinoma of the breast. The British Journal of Surgery, 89(10), 1296-301.
Munot K, et al. Role of Magnetic Resonance Imaging in the Diagnosis and Single-stage Surgical Resection of Invasive Lobular Carcinoma of the Breast. Br J Surg. 2002;89(10):1296-301. PubMed PMID: 12296901.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of magnetic resonance imaging in the diagnosis and single-stage surgical resection of invasive lobular carcinoma of the breast. AU - Munot,K, AU - Dall,B, AU - Achuthan,R, AU - Parkin,G, AU - Lane,S, AU - Horgan,K, PY - 2002/9/26/pubmed PY - 2002/11/26/medline PY - 2002/9/26/entrez SP - 1296 EP - 301 JF - The British journal of surgery JO - Br J Surg VL - 89 IS - 10 N2 - BACKGROUND: Conventional imaging with mammography and ultrasonography has a low sensitivity for diagnosis and a tendency to underestimate the extent of invasive lobular carcinoma (ILC) of the breast. The aim was to determine whether magnetic resonance imaging (MRI) had any advantages for the characterization of ILC. METHODS: Twenty patients with histologically proven ILC underwent preoperative imaging with MRI. MRI was performed to aid detection of malignancy in six patients with a clinically suspicious presentation but normal or indeterminate imaging on mammography and ultrasonography. In 14 patients MRI was performed to determine tumour extent. RESULTS: MRI accurately identified malignancy in five of six patients with normal or indeterminate conventional imaging. In seven of 14 patients in whom MRI was performed to determine tumour extent, it provided significant additional information. These included four patients in whom conventional imaging grossly underestimated tumour size, two patients in whom MRI identified an unsuspected contralateral breast tumour and one patient in whom MRI predicted tumour invasion of the pectoral muscle. The correlation between tumour size on histological examination was better with MRI (r = 0.967) than with mammography (r = 0.663) and ultrasonography (r = 0.673). CONCLUSION: MRI can provide considerable additional information in the detection and characterization of ILC. SN - 0007-1323 UR - https://www.unboundmedicine.com/medline/citation/12296901/Role_of_magnetic_resonance_imaging_in_the_diagnosis_and_single_stage_surgical_resection_of_invasive_lobular_carcinoma_of_the_breast_ L2 - https://academic.oup.com/bjs/article-lookup/doi/10.1046/j.1365-2168.2002.02208.x DB - PRIME DP - Unbound Medicine ER -