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[Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis].
Arerugi. 2002 Aug; 51(8):615-21.A

Abstract

We analyzed the reactivities of a series of purified allergens from Candida albicans (C. albicans) and Malassezia furfur (M. furfur) with IgE antibodies in sera from patients with atopic dermatitis. We compared the specific IgE antibody levels to manganese superoxide dismutase (Mn SOD), cyclophilin, enolase, secretory aspartic protease (SAP 2) and type A mannan from C. albicans and Mn SOD, cyclophilin and Mal f 2 from M. furfur in 21 sera from patients with atopic dermatitis and 20 sera from patients with asthma without atopic dermatitis. The prevalence of IgE antibodies and the mean IgE antibody levels to all of the allergens tested were higher among patients with atopic dermatitis than among those with asthma without atopic dermatitis. More than 50% of patients with atopic dermatitis were IgE antibody-positive to Mn SOD, cyclophilin and type A mannan from C. albicans, and Mn SOD and cyclophilin from M. furfur. The availability of these purified allergens will facilitate studies on the contribution of fungal allergens to the development of atopic dermatitis.

Authors+Show Affiliations

Asako Y
Clinical Research Center for Allergy and Rheumatology, National Sagamihara Hospital.
Saito A
No affiliation info available
Yasueda H
No affiliation info available
Kawaguchi H
No affiliation info available
Akiyama K
No affiliation info available
Endo M
No affiliation info available
Onishi Y
No affiliation info available
Takesako K
No affiliation info available

MeSH

AdultAllergensAntibodies, BacterialAntibodies, FungalCandida albicansDermatitis, AtopicFemaleHumansImmunoglobulin EMalasseziaMale

Pub Type(s)

Journal Article

Language

jpn

PubMed ID

12368565

Citation

Asako, Yoshiko, et al. "[Analysis of IgE Reactivities of Purified Allergens From Candida Albicans and Malassezia Furfur Among Patients With Atopic Dermatitis]." Arerugi = [Allergy], vol. 51, no. 8, 2002, pp. 615-21.
Asako Y, Saito A, Yasueda H, et al. [Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis]. Arerugi. 2002;51(8):615-21.
Asako, Y., Saito, A., Yasueda, H., Kawaguchi, H., Akiyama, K., Endo, M., Onishi, Y., & Takesako, K. (2002). [Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis]. Arerugi = [Allergy], 51(8), 615-21.
Asako Y, et al. [Analysis of IgE Reactivities of Purified Allergens From Candida Albicans and Malassezia Furfur Among Patients With Atopic Dermatitis]. Arerugi. 2002;51(8):615-21. PubMed PMID: 12368565.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Analysis of IgE reactivities of purified allergens from Candida albicans and Malassezia furfur among patients with atopic dermatitis]. AU - Asako,Yoshiko, AU - Saito,Akemi, AU - Yasueda,Hiroshi, AU - Kawaguchi,Hiroshi, AU - Akiyama,Kazuo, AU - Endo,Masahiro, AU - Onishi,Yoshimi, AU - Takesako,Kazutoh, PY - 2002/10/9/pubmed PY - 2002/12/11/medline PY - 2002/10/9/entrez SP - 615 EP - 21 JF - Arerugi = [Allergy] JO - Arerugi VL - 51 IS - 8 N2 - We analyzed the reactivities of a series of purified allergens from Candida albicans (C. albicans) and Malassezia furfur (M. furfur) with IgE antibodies in sera from patients with atopic dermatitis. We compared the specific IgE antibody levels to manganese superoxide dismutase (Mn SOD), cyclophilin, enolase, secretory aspartic protease (SAP 2) and type A mannan from C. albicans and Mn SOD, cyclophilin and Mal f 2 from M. furfur in 21 sera from patients with atopic dermatitis and 20 sera from patients with asthma without atopic dermatitis. The prevalence of IgE antibodies and the mean IgE antibody levels to all of the allergens tested were higher among patients with atopic dermatitis than among those with asthma without atopic dermatitis. More than 50% of patients with atopic dermatitis were IgE antibody-positive to Mn SOD, cyclophilin and type A mannan from C. albicans, and Mn SOD and cyclophilin from M. furfur. The availability of these purified allergens will facilitate studies on the contribution of fungal allergens to the development of atopic dermatitis. SN - 0021-4884 UR - https://www.unboundmedicine.com/medline/citation/12368565/[Analysis_of_IgE_reactivities_of_purified_allergens_from_Candida_albicans_and_Malassezia_furfur_among_patients_with_atopic_dermatitis]_ DB - PRIME DP - Unbound Medicine ER -