Type your tag names separated by a space and hit enter
Viral disease transmitted by laser-generated plume (aerosol).
OBJECTIVETo evaluate the possibility of disease transmission through liberated plume from virally infected tissue that is exposed to the carbon dioxide laser.
DESIGNBovine papillomavirus-induced cutaneous fibropapillomas were exposed to the carbon dioxide laser. Laser settings were within the range of clinically used settings. The laser plume (aerosol) was suctioned and collected and then reinoculated onto the skin of calves.
SETTINGUniversity laboratory research center.
MAIN OUTCOME MEASURESLaser plume viral content and postinoculation tumor growth were analyzed and documented.
RESULTSCollected laser plume contained papillomavirus DNA in all tested laser settings. The viral DNA was most likely encapsulated. Tumors developed at laser plume-inoculated sites for all laser parameter settings. Histological and biochemical analyses revealed that these tumors were infected with the same virus type as present in the laser plume.
CONCLUSIONSLaser plume has been shown, for the first time to our knowledge, to actually transmit disease. Strict care must be maintained by the laser practitioner to minimize potential health risks, especially when treating viral-induced lesions or patients with viral disease.
Department of Dermatology, Chicago, IL 60611, USA. email@example.com, ,
Archives of dermatology 138:10 2002 Oct pg 1303-7
Bovine papillomavirus 1
Disease Models, Animal
Disease Transmission, Infectious
Tumor Virus Infections
Pub Type(s)Comparative Study
Research Support, Non-U.S. Gov't