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Viral disease transmitted by laser-generated plume (aerosol).

Abstract

OBJECTIVE

To evaluate the possibility of disease transmission through liberated plume from virally infected tissue that is exposed to the carbon dioxide laser.

DESIGN

Bovine papillomavirus-induced cutaneous fibropapillomas were exposed to the carbon dioxide laser. Laser settings were within the range of clinically used settings. The laser plume (aerosol) was suctioned and collected and then reinoculated onto the skin of calves.

SETTING

University laboratory research center.

MAIN OUTCOME MEASURES

Laser plume viral content and postinoculation tumor growth were analyzed and documented.

RESULTS

Collected laser plume contained papillomavirus DNA in all tested laser settings. The viral DNA was most likely encapsulated. Tumors developed at laser plume-inoculated sites for all laser parameter settings. Histological and biochemical analyses revealed that these tumors were infected with the same virus type as present in the laser plume.

CONCLUSIONS

Laser plume has been shown, for the first time to our knowledge, to actually transmit disease. Strict care must be maintained by the laser practitioner to minimize potential health risks, especially when treating viral-induced lesions or patients with viral disease.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology, Chicago, IL 60611, USA. j_garden@northwestern.edu

    , ,

    Source

    Archives of dermatology 138:10 2002 Oct pg 1303-7

    MeSH

    Aerosols
    Air Microbiology
    Animals
    Bovine papillomavirus 1
    Carbon Dioxide
    Cattle
    DNA, Viral
    Disease Models, Animal
    Disease Transmission, Infectious
    Equipment Contamination
    Laser Therapy
    Papillomavirus Infections
    Reference Values
    Risk Assessment
    Tumor Virus Infections

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    12374535

    Citation

    TY - JOUR T1 - Viral disease transmitted by laser-generated plume (aerosol). AU - Garden,Jerome M, AU - O'Banion,M Kerry, AU - Bakus,Abnoeal D, AU - Olson,Carl, PY - 2002/10/11/pubmed PY - 2002/11/26/medline PY - 2002/10/11/entrez SP - 1303 EP - 7 JF - Archives of dermatology JO - Arch Dermatol VL - 138 IS - 10 N2 - OBJECTIVE: To evaluate the possibility of disease transmission through liberated plume from virally infected tissue that is exposed to the carbon dioxide laser. DESIGN: Bovine papillomavirus-induced cutaneous fibropapillomas were exposed to the carbon dioxide laser. Laser settings were within the range of clinically used settings. The laser plume (aerosol) was suctioned and collected and then reinoculated onto the skin of calves. SETTING: University laboratory research center. MAIN OUTCOME MEASURES: Laser plume viral content and postinoculation tumor growth were analyzed and documented. RESULTS: Collected laser plume contained papillomavirus DNA in all tested laser settings. The viral DNA was most likely encapsulated. Tumors developed at laser plume-inoculated sites for all laser parameter settings. Histological and biochemical analyses revealed that these tumors were infected with the same virus type as present in the laser plume. CONCLUSIONS: Laser plume has been shown, for the first time to our knowledge, to actually transmit disease. Strict care must be maintained by the laser practitioner to minimize potential health risks, especially when treating viral-induced lesions or patients with viral disease. SN - 0003-987X UR - https://www.unboundmedicine.com/medline/citation/12374535/Viral_disease_transmitted_by_laser_generated_plume__aerosol__ L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/vol/138/pg/1303 ER -