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[Convulsive status secondary to star anise poisoning in a neonate].
An Esp Pediatr. 2002 Oct; 57(4):366-8.AE

Abstract

Despite its potential toxicity, the use of star anise infusions for the treatment of infant colic is firmly rooted in our culture. In the last year, several cases of infants with acute neurological and gastrointestinal symptoms related to the ingestion of large quantities of star-shaped anise have been reported in Spain. We report a 1-month old girl who was admitted to our emergency room with convulsive status after ingesting a considerable amount of star anis administered to relieve possible infant colic. The patient required three repeat doses of diazepam to control the seizures. Because no abnormalities were found and outcome was favorable without anticonvulsant therapy, the clinical symptoms can be attributed to star anise ingestion, which contains potent neurotoxins such as veranisatins. The etiopathogenesis of this process and star anise toxicity are discussed and the need for the regulation of natural products with pharmacological effects which are freely dispensed from drug stores is stressed. Finally, the regulations of the Ministry of Health and Consumption for 2001 concerning the withdrawal of all anise-containing products are presented.

Authors+Show Affiliations

Servicio de Críticos y Urgencias Pediátricas, Departamento de Pediatría. Hospital Universitario Reina Sofía, Facultad de Medicina, Córdoba, España.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

12392673

Citation

Gil Campos, M, et al. "[Convulsive Status Secondary to Star Anise Poisoning in a Neonate]." Anales Espanoles De Pediatria, vol. 57, no. 4, 2002, pp. 366-8.
Gil Campos M, Pérez Navero JL, Ibarra De La Rosa I. [Convulsive status secondary to star anise poisoning in a neonate]. An Esp Pediatr. 2002;57(4):366-8.
Gil Campos, M., Pérez Navero, J. L., & Ibarra De La Rosa, I. (2002). [Convulsive status secondary to star anise poisoning in a neonate]. Anales Espanoles De Pediatria, 57(4), 366-8.
Gil Campos M, Pérez Navero JL, Ibarra De La Rosa I. [Convulsive Status Secondary to Star Anise Poisoning in a Neonate]. An Esp Pediatr. 2002;57(4):366-8. PubMed PMID: 12392673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Convulsive status secondary to star anise poisoning in a neonate]. AU - Gil Campos,M, AU - Pérez Navero,J L, AU - Ibarra De La Rosa,I, PY - 2002/10/24/pubmed PY - 2003/5/31/medline PY - 2002/10/24/entrez SP - 366 EP - 8 JF - Anales espanoles de pediatria JO - An Esp Pediatr VL - 57 IS - 4 N2 - Despite its potential toxicity, the use of star anise infusions for the treatment of infant colic is firmly rooted in our culture. In the last year, several cases of infants with acute neurological and gastrointestinal symptoms related to the ingestion of large quantities of star-shaped anise have been reported in Spain. We report a 1-month old girl who was admitted to our emergency room with convulsive status after ingesting a considerable amount of star anis administered to relieve possible infant colic. The patient required three repeat doses of diazepam to control the seizures. Because no abnormalities were found and outcome was favorable without anticonvulsant therapy, the clinical symptoms can be attributed to star anise ingestion, which contains potent neurotoxins such as veranisatins. The etiopathogenesis of this process and star anise toxicity are discussed and the need for the regulation of natural products with pharmacological effects which are freely dispensed from drug stores is stressed. Finally, the regulations of the Ministry of Health and Consumption for 2001 concerning the withdrawal of all anise-containing products are presented. SN - 0302-4342 UR - https://www.unboundmedicine.com/medline/citation/12392673/[Convulsive_status_secondary_to_star_anise_poisoning_in_a_neonate]_ L2 - https://medlineplus.gov/herbalmedicine.html DB - PRIME DP - Unbound Medicine ER -