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The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report.

Abstract

Recent investigations have shown that bacterial overgrowth of the small intestine is associated with a number of functional somatic disorders, including irritable bowel syndrome (IBS), fibromyalgia, and chronic fatigue syndrome. A number of controlled studies have shown that enteric-coated peppermint oil (ECPO) is of benefit in the treatment of IBS. However, despite evidence of strong antimicrobial activity, ECPO has not been specifically investigated for an effect on small intestinal bacterial overgrowth (SIBO). A case report of a patient with SIBO who showed marked subjective improvement in IBS-like symptoms and significant reductions in hydrogen production after treatment with ECPO is presented. While further investigation is necessary, the results in this case suggest one of the mechanisms by which ECPO improves IBS symptoms is antimicrobial activity in the small intestine.

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  • Authors+Show Affiliations

    ,

    Integrative Care Centre, 3600 Ellesmere Road, Unit 4, Toronto, ON M1C 4Y8, Canada.

    Source

    MeSH

    Adult
    Anti-Bacterial Agents
    Colonic Diseases, Functional
    Female
    Humans
    Intestine, Small
    Plant Oils
    Tablets, Enteric-Coated

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    12410625

    Citation

    Logan, Alan C., and Tracey M. Beaulne. "The Treatment of Small Intestinal Bacterial Overgrowth With Enteric-coated Peppermint Oil: a Case Report." Alternative Medicine Review : a Journal of Clinical Therapeutic, vol. 7, no. 5, 2002, pp. 410-7.
    Logan AC, Beaulne TM. The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report. Altern Med Rev. 2002;7(5):410-7.
    Logan, A. C., & Beaulne, T. M. (2002). The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report. Alternative Medicine Review : a Journal of Clinical Therapeutic, 7(5), pp. 410-7.
    Logan AC, Beaulne TM. The Treatment of Small Intestinal Bacterial Overgrowth With Enteric-coated Peppermint Oil: a Case Report. Altern Med Rev. 2002;7(5):410-7. PubMed PMID: 12410625.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report. AU - Logan,Alan C, AU - Beaulne,Tracey M, PY - 2002/11/2/pubmed PY - 2003/1/22/medline PY - 2002/11/2/entrez SP - 410 EP - 7 JF - Alternative medicine review : a journal of clinical therapeutic JO - Altern Med Rev VL - 7 IS - 5 N2 - Recent investigations have shown that bacterial overgrowth of the small intestine is associated with a number of functional somatic disorders, including irritable bowel syndrome (IBS), fibromyalgia, and chronic fatigue syndrome. A number of controlled studies have shown that enteric-coated peppermint oil (ECPO) is of benefit in the treatment of IBS. However, despite evidence of strong antimicrobial activity, ECPO has not been specifically investigated for an effect on small intestinal bacterial overgrowth (SIBO). A case report of a patient with SIBO who showed marked subjective improvement in IBS-like symptoms and significant reductions in hydrogen production after treatment with ECPO is presented. While further investigation is necessary, the results in this case suggest one of the mechanisms by which ECPO improves IBS symptoms is antimicrobial activity in the small intestine. SN - 1089-5159 UR - https://www.unboundmedicine.com/medline/citation/12410625/full_citation L2 - http://archive.foundationalmedicinereview.com/publications/7/5/410.pdf DB - PRIME DP - Unbound Medicine ER -