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[Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation].
Zhonghua Wai Ke Za Zhi. 2002 Sep; 40(9):647-9.ZW

Abstract

OBJECTIVE

To study the long-term curative effects of suture plus proximal gastric vagotomy (PGV) and suture plus triad-therapy (omeprazole, amoxycillin and flagyl taken orally) for the treatment of duodenal ulcer with acute perforation.

METHODS

Three hundred and twenty-nine patients with duodenal ulcer and acute perforation were treated with 2 different methods, respectively. Method A was suture plus PGV (group A, 153 cases), and method B was suture plus triad-therapy (group B, 176 cases). Follow-up was made by means of correspondence, outpatient reexamination and cooperation with local hospitals in 5 to 8 years after operation. The contents of follow-up included symptom acquisition (such as upper abdominal pain or distention, pyrosis, belch, acid regurgitation, vomiting, diarrhea and conditions of living or working), gastroscopy and Helicobacter pylori (HP) detection. The curative effects were evaluated by the Visick scale.

RESULTS

Three hundred and one patients were followed up (group A 142 and group B 159). According to the Visick scale, 97 (68.3%), 19 (13.4%), 13 (9.15%) and 13 (9.15%) patients in group A, and 31 (19.5%), 28 (17.6%), 24 (15.1%) and 76 (47.8%) in group B were classified as Visick I, II, III and IV respectively (Z = -9.818, P < 0.01). As for HP detection, there were 130 (91.5%) patients in group A and 94 (59.1%) in group B (chi(2) = 41.438, P < 0.01).

CONCLUSIONS

The long-term curative effects of suture plus PGV were superior to those of suture plus triad-therapy for duodenal ulcer with acute perforation although HP positive rate was higher in group A than in group B. HP infection is one of the etiological factors of duodenal ulcer. The increased excitability of the vagus nerve remains to play an important role in duodenal ulcer.

Authors+Show Affiliations

Department of General Surgery, Third Hospital of Sun Yat-Sen University, Guangzhou 510630, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

12411130

Citation

Xu, Ruiyun, et al. "[Long-term Curative Effects of Suture Plus Proximal Gastric Vagotomy or Triad-therapy for Duodenal Ulcer With Acute Perforation]." Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], vol. 40, no. 9, 2002, pp. 647-9.
Xu R, Fang L, Jiang X, et al. [Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation]. Zhonghua Wai Ke Za Zhi. 2002;40(9):647-9.
Xu, R., Fang, L., Jiang, X., Wan, Y., Huang, S., Jiang, K., Lin, N., & Pan, W. (2002). [Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], 40(9), 647-9.
Xu R, et al. [Long-term Curative Effects of Suture Plus Proximal Gastric Vagotomy or Triad-therapy for Duodenal Ulcer With Acute Perforation]. Zhonghua Wai Ke Za Zhi. 2002;40(9):647-9. PubMed PMID: 12411130.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation]. AU - Xu,Ruiyun, AU - Fang,Li, AU - Jiang,Xiaochun, AU - Wan,Yueping, AU - Huang,Shaowei, AU - Jiang,Kesong, AU - Lin,Nan, AU - Pan,Weidong, PY - 2002/11/2/pubmed PY - 2003/7/24/medline PY - 2002/11/2/entrez SP - 647 EP - 9 JF - Zhonghua wai ke za zhi [Chinese journal of surgery] JO - Zhonghua Wai Ke Za Zhi VL - 40 IS - 9 N2 - OBJECTIVE: To study the long-term curative effects of suture plus proximal gastric vagotomy (PGV) and suture plus triad-therapy (omeprazole, amoxycillin and flagyl taken orally) for the treatment of duodenal ulcer with acute perforation. METHODS: Three hundred and twenty-nine patients with duodenal ulcer and acute perforation were treated with 2 different methods, respectively. Method A was suture plus PGV (group A, 153 cases), and method B was suture plus triad-therapy (group B, 176 cases). Follow-up was made by means of correspondence, outpatient reexamination and cooperation with local hospitals in 5 to 8 years after operation. The contents of follow-up included symptom acquisition (such as upper abdominal pain or distention, pyrosis, belch, acid regurgitation, vomiting, diarrhea and conditions of living or working), gastroscopy and Helicobacter pylori (HP) detection. The curative effects were evaluated by the Visick scale. RESULTS: Three hundred and one patients were followed up (group A 142 and group B 159). According to the Visick scale, 97 (68.3%), 19 (13.4%), 13 (9.15%) and 13 (9.15%) patients in group A, and 31 (19.5%), 28 (17.6%), 24 (15.1%) and 76 (47.8%) in group B were classified as Visick I, II, III and IV respectively (Z = -9.818, P < 0.01). As for HP detection, there were 130 (91.5%) patients in group A and 94 (59.1%) in group B (chi(2) = 41.438, P < 0.01). CONCLUSIONS: The long-term curative effects of suture plus PGV were superior to those of suture plus triad-therapy for duodenal ulcer with acute perforation although HP positive rate was higher in group A than in group B. HP infection is one of the etiological factors of duodenal ulcer. The increased excitability of the vagus nerve remains to play an important role in duodenal ulcer. SN - 0529-5815 UR - https://www.unboundmedicine.com/medline/citation/12411130/[Long_term_curative_effects_of_suture_plus_proximal_gastric_vagotomy_or_triad_therapy_for_duodenal_ulcer_with_acute_perforation]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0529-5815&amp;year=2002&amp;vol=40&amp;issue=9&amp;fpage=647 DB - PRIME DP - Unbound Medicine ER -