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Cannabidiol: an overview of some pharmacological aspects.
J Clin Pharmacol. 2002 11; 42(S1):11S-19S.JC

Abstract

Over the past few years, considerable attention has focused on cannabidiol (CBD), a major nonpsychotropic constituent of cannabis. The authors present a review on the chemistry of CBD and discuss the anticonvulsive, antianxiety, antipsychotic, antinausea, and antirheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors, and its mechanism of action is yet unknown. It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect.

Authors+Show Affiliations

Deportment of Medicinal Chemistry and Natural Products, Hebrew University of Jerusalem, Israel.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

12412831

Citation

Mechoulam, Raphael, et al. "Cannabidiol: an Overview of some Pharmacological Aspects." Journal of Clinical Pharmacology, vol. 42, no. S1, 2002, 11S-19S.
Mechoulam R, Parker LA, Gallily R. Cannabidiol: an overview of some pharmacological aspects. J Clin Pharmacol. 2002;42(S1):11S-19S.
Mechoulam, R., Parker, L. A., & Gallily, R. (2002). Cannabidiol: an overview of some pharmacological aspects. Journal of Clinical Pharmacology, 42(S1), 11S-19S.
Mechoulam R, Parker LA, Gallily R. Cannabidiol: an Overview of some Pharmacological Aspects. J Clin Pharmacol. 2002;42(S1):11S-19S. PubMed PMID: 12412831.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol: an overview of some pharmacological aspects. AU - Mechoulam,Raphael, AU - Parker,Linda A, AU - Gallily,Ruth, PY - 2002/11/5/pubmed PY - 2003/3/13/medline PY - 2002/11/5/entrez SP - 11S EP - 19S JF - Journal of clinical pharmacology JO - J Clin Pharmacol VL - 42 IS - S1 N2 - Over the past few years, considerable attention has focused on cannabidiol (CBD), a major nonpsychotropic constituent of cannabis. The authors present a review on the chemistry of CBD and discuss the anticonvulsive, antianxiety, antipsychotic, antinausea, and antirheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors, and its mechanism of action is yet unknown. It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect. SN - 0091-2700 UR - https://www.unboundmedicine.com/medline/citation/12412831/Cannabidiol:_an_overview_of_some_pharmacological_aspects_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0091-2700&date=2002&volume=42&issue=S1&spage=11S DB - PRIME DP - Unbound Medicine ER -