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Nonacute (residual) neuropsychological effects of cannabis use: a qualitative analysis and systematic review.

Abstract

Because there is a possibility that cannabis or cannabis-like molecules might be used as treatments for certain conditions in the future, it becomes important to consider the possible adverse effects of these compounds. In this paper, the authors review the evidence for persisting effects of nonacute cannabis use on the central nervous system, as reflected by alteration in neuropsychological performance. From the 40 articles that met criteria for inclusion in this review, the authors could not detect consistent evidence for persisting neuropsychological deficits in cannabis users; however, 22 of the 40 studies reported at least some subtle impairments. The inability to reach a firm conclusion results largely from methodological limitations inherent in most studies. These are considered in detail to inform future studies on (nonacute) consequences of cannabis consumption on cognitive abilities.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Psychiatry, Center for Medicinal Cannabis Research, University of California, San Diego 92103, USA.

    ,

    Source

    Journal of clinical pharmacology 42:S1 2002 11 pg 48S-57S

    MeSH

    Cognition Disorders
    Humans
    Marijuana Abuse
    Marijuana Smoking
    Neuropsychological Tests

    Pub Type(s)

    Journal Article
    Meta-Analysis
    Systematic Review

    Language

    eng

    PubMed ID

    12412836

    Citation

    Gonzalez, Raul, et al. "Nonacute (residual) Neuropsychological Effects of Cannabis Use: a Qualitative Analysis and Systematic Review." Journal of Clinical Pharmacology, vol. 42, no. S1, 2002, 48S-57S.
    Gonzalez R, Carey C, Grant I. Nonacute (residual) neuropsychological effects of cannabis use: a qualitative analysis and systematic review. J Clin Pharmacol. 2002;42(S1):48S-57S.
    Gonzalez, R., Carey, C., & Grant, I. (2002). Nonacute (residual) neuropsychological effects of cannabis use: a qualitative analysis and systematic review. Journal of Clinical Pharmacology, 42(S1), 48S-57S.
    Gonzalez R, Carey C, Grant I. Nonacute (residual) Neuropsychological Effects of Cannabis Use: a Qualitative Analysis and Systematic Review. J Clin Pharmacol. 2002;42(S1):48S-57S. PubMed PMID: 12412836.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Nonacute (residual) neuropsychological effects of cannabis use: a qualitative analysis and systematic review. AU - Gonzalez,Raul, AU - Carey,Catherine, AU - Grant,Igor, PY - 2002/11/5/pubmed PY - 2003/3/13/medline PY - 2002/11/5/entrez SP - 48S EP - 57S JF - Journal of clinical pharmacology JO - J Clin Pharmacol VL - 42 IS - S1 N2 - Because there is a possibility that cannabis or cannabis-like molecules might be used as treatments for certain conditions in the future, it becomes important to consider the possible adverse effects of these compounds. In this paper, the authors review the evidence for persisting effects of nonacute cannabis use on the central nervous system, as reflected by alteration in neuropsychological performance. From the 40 articles that met criteria for inclusion in this review, the authors could not detect consistent evidence for persisting neuropsychological deficits in cannabis users; however, 22 of the 40 studies reported at least some subtle impairments. The inability to reach a firm conclusion results largely from methodological limitations inherent in most studies. These are considered in detail to inform future studies on (nonacute) consequences of cannabis consumption on cognitive abilities. SN - 0091-2700 UR - https://www.unboundmedicine.com/medline/citation/12412836/Nonacute__residual__neuropsychological_effects_of_cannabis_use:_a_qualitative_analysis_and_systematic_review_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0091-2700&date=2002&volume=42&issue=S1&spage=48S DB - PRIME DP - Unbound Medicine ER -