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[Obesity and gastroesophageal reflux disease].
Rev Invest Clin 2002 Jul-Aug; 54(4):320-7RI

Abstract

INTRODUCTION

Obesity is a condition that has been associated with gastroesophageal reflux disease (GERD), however, a cause-effect relationship has not been established.

AIM

To analyze current evidence evaluating the relationship between obesity and GERD, as well as the impact of hypocaloric diets and bariatric surgery in gastroesophageal reflux symptoms.

MATERIAL AND METHODS

An electronic search in the MEDLINE was performed, looking for information published during the past 15 years: Cohort studies, case-control studies, case series and case reports, including the following key words: "heartburn", "reflux", "gerd", "reflux esophagitis", "obesity", "overweight", "diet", "bariatric surgery" were analized.

RESULTS

Thirty-one articles were included. These studies were classified according to the diagnostic method of GERD (i.e., manometry, 24-hour pH monitoring, esophageal transit, endoscopy) and type of bariatric surgery: Adjustable gastric banding (AGB), vertical banded gastroplasty (VBG), and Roux-en-Y gastric bypass (RYGB), or anti-reflux procedure.

CONCLUSIONS

Most studies suggest that obesity is a condition predisposing to the development of GERD. However, there are no studies that correlate the degree of obesity with the symptoms of reflux. Hypotonic lower esophageal sphincter, ineffective esophageal motility and presence of hiatal hernia are the pathophysiological mechanisms proposed as inductors of gastroesophageal reflux among obese patients. AGB and VBG seem to induce postoperative esophagitis in some patients, but RYGB has shown to be effective to control GERD symptoms. Overweight and obesity do not seem to affect the results of antireflux surgery. The impact of body weight loss on GERD following hypocaloric diets requires further investigation.

Authors+Show Affiliations

Departamentos de Gastroenterología y Cirugía. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, D.F.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

spa

PubMed ID

12415956

Citation

Gómez Escudero, Octavio, et al. "[Obesity and Gastroesophageal Reflux Disease]." Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, vol. 54, no. 4, 2002, pp. 320-7.
Gómez Escudero O, Herrera Hernández MF, Valdovinos Díaz MA. [Obesity and gastroesophageal reflux disease]. Rev Invest Clin. 2002;54(4):320-7.
Gómez Escudero, O., Herrera Hernández, M. F., & Valdovinos Díaz, M. A. (2002). [Obesity and gastroesophageal reflux disease]. Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, 54(4), pp. 320-7.
Gómez Escudero O, Herrera Hernández MF, Valdovinos Díaz MA. [Obesity and Gastroesophageal Reflux Disease]. Rev Invest Clin. 2002;54(4):320-7. PubMed PMID: 12415956.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Obesity and gastroesophageal reflux disease]. AU - Gómez Escudero,Octavio, AU - Herrera Hernández,Miguel F, AU - Valdovinos Díaz,Miguel A, PY - 2002/11/6/pubmed PY - 2003/1/24/medline PY - 2002/11/6/entrez SP - 320 EP - 7 JF - Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion JO - Rev. Invest. Clin. VL - 54 IS - 4 N2 - INTRODUCTION: Obesity is a condition that has been associated with gastroesophageal reflux disease (GERD), however, a cause-effect relationship has not been established. AIM: To analyze current evidence evaluating the relationship between obesity and GERD, as well as the impact of hypocaloric diets and bariatric surgery in gastroesophageal reflux symptoms. MATERIAL AND METHODS: An electronic search in the MEDLINE was performed, looking for information published during the past 15 years: Cohort studies, case-control studies, case series and case reports, including the following key words: "heartburn", "reflux", "gerd", "reflux esophagitis", "obesity", "overweight", "diet", "bariatric surgery" were analized. RESULTS: Thirty-one articles were included. These studies were classified according to the diagnostic method of GERD (i.e., manometry, 24-hour pH monitoring, esophageal transit, endoscopy) and type of bariatric surgery: Adjustable gastric banding (AGB), vertical banded gastroplasty (VBG), and Roux-en-Y gastric bypass (RYGB), or anti-reflux procedure. CONCLUSIONS: Most studies suggest that obesity is a condition predisposing to the development of GERD. However, there are no studies that correlate the degree of obesity with the symptoms of reflux. Hypotonic lower esophageal sphincter, ineffective esophageal motility and presence of hiatal hernia are the pathophysiological mechanisms proposed as inductors of gastroesophageal reflux among obese patients. AGB and VBG seem to induce postoperative esophagitis in some patients, but RYGB has shown to be effective to control GERD symptoms. Overweight and obesity do not seem to affect the results of antireflux surgery. The impact of body weight loss on GERD following hypocaloric diets requires further investigation. SN - 0034-8376 UR - https://www.unboundmedicine.com/medline/citation/12415956/[Obesity_and_gastroesophageal_reflux_disease]_ L2 - https://medlineplus.gov/gerd.html DB - PRIME DP - Unbound Medicine ER -