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Independent actions on fear circuits may lead to therapeutic synergy for anxiety when combining serotonergic and GABAergic agents.
J Clin Psychiatry. 2002 Oct; 63(10):854-5.JC

Abstract

ISSUE

Both serotonin and GABA powerfully regulate the neuroanatomical circuit that mediates fear in anxiety disorders. This suggests that use of pharmacotherapies acting on both systems may provide synergistic therapeutic actions.

Authors+Show Affiliations

Neuroscience Education Institute, Carlsbad, CA 92009, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12416593

Citation

Stahl, Stephen M.. "Independent Actions On Fear Circuits May Lead to Therapeutic Synergy for Anxiety when Combining Serotonergic and GABAergic Agents." The Journal of Clinical Psychiatry, vol. 63, no. 10, 2002, pp. 854-5.
Stahl SM. Independent actions on fear circuits may lead to therapeutic synergy for anxiety when combining serotonergic and GABAergic agents. J Clin Psychiatry. 2002;63(10):854-5.
Stahl, S. M. (2002). Independent actions on fear circuits may lead to therapeutic synergy for anxiety when combining serotonergic and GABAergic agents. The Journal of Clinical Psychiatry, 63(10), 854-5.
Stahl SM. Independent Actions On Fear Circuits May Lead to Therapeutic Synergy for Anxiety when Combining Serotonergic and GABAergic Agents. J Clin Psychiatry. 2002;63(10):854-5. PubMed PMID: 12416593.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Independent actions on fear circuits may lead to therapeutic synergy for anxiety when combining serotonergic and GABAergic agents. A1 - Stahl,Stephen M, PY - 2002/11/6/pubmed PY - 2002/11/26/medline PY - 2002/11/6/entrez SP - 854 EP - 5 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 63 IS - 10 N2 - ISSUE: Both serotonin and GABA powerfully regulate the neuroanatomical circuit that mediates fear in anxiety disorders. This suggests that use of pharmacotherapies acting on both systems may provide synergistic therapeutic actions. SN - 0160-6689 UR - https://www.unboundmedicine.com/medline/citation/12416593/Independent_actions_on_fear_circuits_may_lead_to_therapeutic_synergy_for_anxiety_when_combining_serotonergic_and_GABAergic_agents_ L2 - http://www.psychiatrist.com/jcp/article/pages/2002/v63n10/v63n1001.aspx DB - PRIME DP - Unbound Medicine ER -