TY - JOUR T1 - [Clinical characteristics and diagnosis of Pneumocystis carinii pneumonia (PCP) in patients with the acquired immunodeficiency syndrome (AIDS)]. AU - Zhang,Ke, AU - Ma,Daqing, AU - Xu,Bin, AU - Zhao,Dawei, AU - Wu,Hao, AU - Hua,Liwei, AU - Qin,Shulin, AU - Xu,Lianzhi, PY - 2002/11/12/pubmed PY - 2003/1/31/medline PY - 2002/11/12/entrez SP - 475 EP - 7 JF - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases JO - Zhonghua Jie He He Hu Xi Za Zhi VL - 25 IS - 8 N2 - OBJECTIVE: To explore the clinical characteristics and the diagnostic methods for PCP in patients with AIDS. METHODS: Twelve cases of AIDS associated PCP confirmed by sputum polymerase chain reaction (PCR) were analyzed. RESULTS: Tuberculosis was found in 4 cases and pneumonia in 1 case of PCP. Sputum PCR was positive in all the 12 cases, of them blood PCR was positive in 9, Gomori methenamine silver stain (GMS) positive in 5 and Giemsa stain positive in 6 cases. The CD(4)(+) lymphocyte count was (5 approximately 155) x 10(6)/L, with a mean of (51 +/- 48) x 10(6)/L; the number of CD(4)(+) cells less than 100 x 10(6)/L in 10 cases (83%) with 9 cases (75%) less than 50 x 10(6)/L. The CD(4)(+)/CD(8)(+) ratio was 0.01 approximately 0.29. CONCLUSIONS: PCP was common in patients with advanced AIDS and often co-infected with other opportunistic infections such as tuberculosis. A diagnosis of PCP should be considered if sputum PCR is positive and typical clinical manifestations are present in patients with AIDS. SN - 1001-0939 UR - https://www.unboundmedicine.com/medline/citation/12425833/[Clinical_characteristics_and_diagnosis_of_Pneumocystis_carinii_pneumonia__PCP__in_patients_with_the_acquired_immunodeficiency_syndrome__AIDS_]_ DB - PRIME DP - Unbound Medicine ER -