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Diagnostic accuracy of the atopy patch test and the skin-prick test for the diagnosis of food allergy in young children with atopic eczema/dermatitis syndrome.
Acta Paediatr 2002; 91(10):1044-9AP

Abstract

AIM

To evaluate the diagnostic value of the skin-prick test and the atopy patch test in diagnosing basic food allergy in young children suffering from atopic eczema/dermatitis syndrome.

METHODS

141 children, the majority under 2 y of age (mean 16 mo) with atopic eczema/dermatitis syndrome were investigated using skin-prick and atopy patch tests for milk, egg, wheat and rye. Open diagnostic elimination challenge was done since this has been reported to be a reliable method in young children.

RESULTS

A positive challenge response was found to milk in 63 (45%), egg in 78 (55%), wheat in 61 (43%) and rye in 61 (43%). Sensitivity/specificity of the atopy patch test was 60%/97% for milk, 71%/97% for egg, 90%/94% for wheat and 93%/90% for rye. For the skin-prick test the corresponding figures were 41%/99%, 60%/97%, 13%/98% and 15%/99%.

CONCLUSION

Patch testing was found to be a more sensitive method than the skin-prick test in diagnosing food allergy in children with atopic eczema/dermatitis syndrome, especially in those under 2 y of age. Many children with a negative skin-prick test result have a positive patch test result, especially in the case of cereals. A diagnosis of food allergy should be confirmed by elimination and in the research setting also by challenge.

Authors+Show Affiliations

Department of Pediatrics, Vrinnevi Hospital, Norrköping, Sweden. leif.stromberg@lio.se

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12434888

Citation

Strömberg, L. "Diagnostic Accuracy of the Atopy Patch Test and the Skin-prick Test for the Diagnosis of Food Allergy in Young Children With Atopic Eczema/dermatitis Syndrome." Acta Paediatrica (Oslo, Norway : 1992), vol. 91, no. 10, 2002, pp. 1044-9.
Strömberg L. Diagnostic accuracy of the atopy patch test and the skin-prick test for the diagnosis of food allergy in young children with atopic eczema/dermatitis syndrome. Acta Paediatr. 2002;91(10):1044-9.
Strömberg, L. (2002). Diagnostic accuracy of the atopy patch test and the skin-prick test for the diagnosis of food allergy in young children with atopic eczema/dermatitis syndrome. Acta Paediatrica (Oslo, Norway : 1992), 91(10), pp. 1044-9.
Strömberg L. Diagnostic Accuracy of the Atopy Patch Test and the Skin-prick Test for the Diagnosis of Food Allergy in Young Children With Atopic Eczema/dermatitis Syndrome. Acta Paediatr. 2002;91(10):1044-9. PubMed PMID: 12434888.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic accuracy of the atopy patch test and the skin-prick test for the diagnosis of food allergy in young children with atopic eczema/dermatitis syndrome. A1 - Strömberg,L, PY - 2002/11/19/pubmed PY - 2003/2/22/medline PY - 2002/11/19/entrez SP - 1044 EP - 9 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 91 IS - 10 N2 - AIM: To evaluate the diagnostic value of the skin-prick test and the atopy patch test in diagnosing basic food allergy in young children suffering from atopic eczema/dermatitis syndrome. METHODS: 141 children, the majority under 2 y of age (mean 16 mo) with atopic eczema/dermatitis syndrome were investigated using skin-prick and atopy patch tests for milk, egg, wheat and rye. Open diagnostic elimination challenge was done since this has been reported to be a reliable method in young children. RESULTS: A positive challenge response was found to milk in 63 (45%), egg in 78 (55%), wheat in 61 (43%) and rye in 61 (43%). Sensitivity/specificity of the atopy patch test was 60%/97% for milk, 71%/97% for egg, 90%/94% for wheat and 93%/90% for rye. For the skin-prick test the corresponding figures were 41%/99%, 60%/97%, 13%/98% and 15%/99%. CONCLUSION: Patch testing was found to be a more sensitive method than the skin-prick test in diagnosing food allergy in children with atopic eczema/dermatitis syndrome, especially in those under 2 y of age. Many children with a negative skin-prick test result have a positive patch test result, especially in the case of cereals. A diagnosis of food allergy should be confirmed by elimination and in the research setting also by challenge. SN - 0803-5253 UR - https://www.unboundmedicine.com/medline/citation/12434888/Diagnostic_accuracy_of_the_atopy_patch_test_and_the_skin_prick_test_for_the_diagnosis_of_food_allergy_in_young_children_with_atopic_eczema/dermatitis_syndrome_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0803-5253&date=2002&volume=91&issue=10&spage=1044 DB - PRIME DP - Unbound Medicine ER -