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Screening for thyroid disorders in asymptomatic adults from Brazilian populations.
Sao Paulo Med J. 2002 Sep 02; 120(5):146-51.SP

Abstract

Advances in thyroid disorder diagnosis have created new thyroid disorder categories such as subclinical hyperthyroidism and subclinical hypothyroidism. In the 1980s, immunometric assaying for thyroid stimulating hormone (TSH) emerged and became defined as the most cost-effective test in thyroid disorder screening. The second step in the screening of thyroid disorders is to determine free thyroxine (FT4), and cost-effective methods for its detection are now available. Using TSH and FT4, it is possible to determine four situations: clinical hyperthyroidism, clinical hypothyroidism, subclinical hyperthyroidism and subclinical hypothyroidism. Subclinical hypothyroidism can be a strong indicator of risk for atherosclerosis and myocardial infarction in elderly women. Cardiovascular mortality among Brazilian women is one of the highest in the Western world. The best-known risk factors for cardiovascular diseases are high blood pressure, smoking, diabetes, and hypercholesterolemia. Although these are recognized as primary risk factors, there are other risk factors that could be identified as primordial risk factors. This may be the case for subclinical hypothyroidism. Early detection of thyroid disorders in women over fifty could be a highly cost-effective option in the prevention of cardiovascular disorders among Brazilian women.

Authors+Show Affiliations

Departamento de Clínica Médica, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil. isabensenor@hcnet.usp.br

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12436151

Citation

Bensenor, Isabela. "Screening for Thyroid Disorders in Asymptomatic Adults From Brazilian Populations." Sao Paulo Medical Journal = Revista Paulista De Medicina, vol. 120, no. 5, 2002, pp. 146-51.
Bensenor I. Screening for thyroid disorders in asymptomatic adults from Brazilian populations. Sao Paulo Med J. 2002;120(5):146-51.
Bensenor, I. (2002). Screening for thyroid disorders in asymptomatic adults from Brazilian populations. Sao Paulo Medical Journal = Revista Paulista De Medicina, 120(5), 146-51.
Bensenor I. Screening for Thyroid Disorders in Asymptomatic Adults From Brazilian Populations. Sao Paulo Med J. 2002 Sep 2;120(5):146-51. PubMed PMID: 12436151.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for thyroid disorders in asymptomatic adults from Brazilian populations. A1 - Bensenor,Isabela, PY - 2002/11/19/pubmed PY - 2002/12/21/medline PY - 2002/11/19/entrez SP - 146 EP - 51 JF - Sao Paulo medical journal = Revista paulista de medicina JO - Sao Paulo Med J VL - 120 IS - 5 N2 - Advances in thyroid disorder diagnosis have created new thyroid disorder categories such as subclinical hyperthyroidism and subclinical hypothyroidism. In the 1980s, immunometric assaying for thyroid stimulating hormone (TSH) emerged and became defined as the most cost-effective test in thyroid disorder screening. The second step in the screening of thyroid disorders is to determine free thyroxine (FT4), and cost-effective methods for its detection are now available. Using TSH and FT4, it is possible to determine four situations: clinical hyperthyroidism, clinical hypothyroidism, subclinical hyperthyroidism and subclinical hypothyroidism. Subclinical hypothyroidism can be a strong indicator of risk for atherosclerosis and myocardial infarction in elderly women. Cardiovascular mortality among Brazilian women is one of the highest in the Western world. The best-known risk factors for cardiovascular diseases are high blood pressure, smoking, diabetes, and hypercholesterolemia. Although these are recognized as primary risk factors, there are other risk factors that could be identified as primordial risk factors. This may be the case for subclinical hypothyroidism. Early detection of thyroid disorders in women over fifty could be a highly cost-effective option in the prevention of cardiovascular disorders among Brazilian women. SN - 1516-3180 UR - https://www.unboundmedicine.com/medline/citation/12436151/Screening_for_thyroid_disorders_in_asymptomatic_adults_from_Brazilian_populations_ L2 - https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802002000500005&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -