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[Variation of the thyrotropin-releasing-hormone (TRH) stimulated thyrotropin (TSH) response in comparison with the tyhroid-gland-suppression test and the triiodothyronine (T3) and thyroxine (T4) blood levels in the so-called euthyroid endocrine ophthalmopathy].
Endokrinologie. 1975 Sep; 66(1):67-73.E

Abstract

21 patients with active signs of euthyroid Graves' disease were given 400 mug thyrotropin-releasing hormone (TRH) i.v. All subjects with unresponsiveness to TRH had a nonsuppressible thyroidal 131I-uptake. On the basis of serum total T3 14 patients were hyperthyroid, 2 more had an elevated value of free T3. 4 patients with normal total T3 and nonsuppressible 131I-uptake were unresponsive to TRH, in 2 of them the free T3 fraction was elevated, however. 4 subjects with nonsuppressible 131I-uptake had a TRH stimulated TSH response. 2 of these subjects had hyperthyroid values of free and total T3 in serum and responded to TRH with an exaggerate TSH increment. The variations of TRH responsiveness may demonstrate a different threshold of the pituitary and the peripheral T3 receptors.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

1243821

Citation

Wenzel, K W.. "[Variation of the Thyrotropin-releasing-hormone (TRH) Stimulated Thyrotropin (TSH) Response in Comparison With the Tyhroid-gland-suppression Test and the Triiodothyronine (T3) and Thyroxine (T4) Blood Levels in the So-called Euthyroid Endocrine Ophthalmopathy]." Endokrinologie, vol. 66, no. 1, 1975, pp. 67-73.
Wenzel KW. [Variation of the thyrotropin-releasing-hormone (TRH) stimulated thyrotropin (TSH) response in comparison with the tyhroid-gland-suppression test and the triiodothyronine (T3) and thyroxine (T4) blood levels in the so-called euthyroid endocrine ophthalmopathy]. Endokrinologie. 1975;66(1):67-73.
Wenzel, K. W. (1975). [Variation of the thyrotropin-releasing-hormone (TRH) stimulated thyrotropin (TSH) response in comparison with the tyhroid-gland-suppression test and the triiodothyronine (T3) and thyroxine (T4) blood levels in the so-called euthyroid endocrine ophthalmopathy]. Endokrinologie, 66(1), 67-73.
Wenzel KW. [Variation of the Thyrotropin-releasing-hormone (TRH) Stimulated Thyrotropin (TSH) Response in Comparison With the Tyhroid-gland-suppression Test and the Triiodothyronine (T3) and Thyroxine (T4) Blood Levels in the So-called Euthyroid Endocrine Ophthalmopathy]. Endokrinologie. 1975;66(1):67-73. PubMed PMID: 1243821.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Variation of the thyrotropin-releasing-hormone (TRH) stimulated thyrotropin (TSH) response in comparison with the tyhroid-gland-suppression test and the triiodothyronine (T3) and thyroxine (T4) blood levels in the so-called euthyroid endocrine ophthalmopathy]. A1 - Wenzel,K W, PY - 1975/9/1/pubmed PY - 1975/9/1/medline PY - 1975/9/1/entrez SP - 67 EP - 73 JF - Endokrinologie JO - Endokrinologie VL - 66 IS - 1 N2 - 21 patients with active signs of euthyroid Graves' disease were given 400 mug thyrotropin-releasing hormone (TRH) i.v. All subjects with unresponsiveness to TRH had a nonsuppressible thyroidal 131I-uptake. On the basis of serum total T3 14 patients were hyperthyroid, 2 more had an elevated value of free T3. 4 patients with normal total T3 and nonsuppressible 131I-uptake were unresponsive to TRH, in 2 of them the free T3 fraction was elevated, however. 4 subjects with nonsuppressible 131I-uptake had a TRH stimulated TSH response. 2 of these subjects had hyperthyroid values of free and total T3 in serum and responded to TRH with an exaggerate TSH increment. The variations of TRH responsiveness may demonstrate a different threshold of the pituitary and the peripheral T3 receptors. SN - 0013-7251 UR - https://www.unboundmedicine.com/medline/citation/1243821/[Variation_of_the_thyrotropin_releasing_hormone__TRH__stimulated_thyrotropin__TSH__response_in_comparison_with_the_tyhroid_gland_suppression_test_and_the_triiodothyronine__T3__and_thyroxine__T4__blood_levels_in_the_so_called_euthyroid_endocrine_ophthalmopathy]_ DB - PRIME DP - Unbound Medicine ER -
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