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Polypoid endometrial adenomyoma in a postmenopausal woman, mimicking cervical cancer, associated with ovarian thecoma.
Arch Gynecol Obstet. 2002 Dec; 267(2):101-3.AG

Abstract

PURPOSE

Atypical polypoid adenomyoma (APA) usually occurs in premenopausal women and arises from the endometrium. APAs protruding into the external os may lead to diagnostic problems.

CASE

We present a case of APA in a 62-year-old postmenopausal woman, prolapsing through the external os, clinically mimicking cervical cancer FIGO IB2 (4.5 cmx3 cmx3 cm). Histologically the tumor was composed of endometrioid-like with slight cellular atypia and endocervical-type mucinous glands admixed with smooth muscle bundles, exhibiting low Ki-67 antigen immunostaining. The the left adnexa contained an ovarian thecoma.

CONCLUSIONS

To the best of our knowledge, this is the first case of APA in a postmenopausal woman, mimicking cervical cancer and associated with ovarian thecoma. Pathogenetically it is proposed, that hyperestrogenism and, in the present case accompanied by progestin production of questionable source, may play an important role in the development of APAs with the admixture of endometrial and endocervical glands.

Links

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Authors+Show Affiliations

Horn LC
Institute of Pathology, University of Leipzig, Liebigstrasse 26, D-04103 Leipzig, Germany. horn@medizin.uni-leipzig.de
Fischer U
No affiliation info available
Höckel M
No affiliation info available

MeSH

AdenomyomaDiagnosis, DifferentialEndometrial NeoplasmsFemaleHumansHysterectomyMiddle AgedNeoplasms, Second PrimaryOvarian NeoplasmsPolypsPostmenopauseThecomaUterine Cervical Neoplasms

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

12439557

Citation

Horn, L-C, et al. "Polypoid Endometrial Adenomyoma in a Postmenopausal Woman, Mimicking Cervical Cancer, Associated With Ovarian Thecoma." Archives of Gynecology and Obstetrics, vol. 267, no. 2, 2002, pp. 101-3.
Horn LC, Fischer U, Höckel M. Polypoid endometrial adenomyoma in a postmenopausal woman, mimicking cervical cancer, associated with ovarian thecoma. Arch Gynecol Obstet. 2002;267(2):101-3.
Horn, L. C., Fischer, U., & Höckel, M. (2002). Polypoid endometrial adenomyoma in a postmenopausal woman, mimicking cervical cancer, associated with ovarian thecoma. Archives of Gynecology and Obstetrics, 267(2), 101-3.
Horn LC, Fischer U, Höckel M. Polypoid Endometrial Adenomyoma in a Postmenopausal Woman, Mimicking Cervical Cancer, Associated With Ovarian Thecoma. Arch Gynecol Obstet. 2002;267(2):101-3. PubMed PMID: 12439557.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Polypoid endometrial adenomyoma in a postmenopausal woman, mimicking cervical cancer, associated with ovarian thecoma. AU - Horn,L-C, AU - Fischer,U, AU - Höckel,M, PY - 2002/11/20/pubmed PY - 2003/5/8/medline PY - 2002/11/20/entrez SP - 101 EP - 3 JF - Archives of gynecology and obstetrics JO - Arch Gynecol Obstet VL - 267 IS - 2 N2 - PURPOSE: Atypical polypoid adenomyoma (APA) usually occurs in premenopausal women and arises from the endometrium. APAs protruding into the external os may lead to diagnostic problems. CASE: We present a case of APA in a 62-year-old postmenopausal woman, prolapsing through the external os, clinically mimicking cervical cancer FIGO IB2 (4.5 cmx3 cmx3 cm). Histologically the tumor was composed of endometrioid-like with slight cellular atypia and endocervical-type mucinous glands admixed with smooth muscle bundles, exhibiting low Ki-67 antigen immunostaining. The the left adnexa contained an ovarian thecoma. CONCLUSIONS: To the best of our knowledge, this is the first case of APA in a postmenopausal woman, mimicking cervical cancer and associated with ovarian thecoma. Pathogenetically it is proposed, that hyperestrogenism and, in the present case accompanied by progestin production of questionable source, may play an important role in the development of APAs with the admixture of endometrial and endocervical glands. SN - 0932-0067 UR - https://www.unboundmedicine.com/medline/citation/12439557/Polypoid_endometrial_adenomyoma_in_a_postmenopausal_woman_mimicking_cervical_cancer_associated_with_ovarian_thecoma_ L2 - https://dx.doi.org/10.1007/s00404-001-0253-8 DB - PRIME DP - Unbound Medicine ER -