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Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata.
J Nat Prod. 2002 Nov; 65(11):1526-9.JN

Abstract

Two new myricetin glycosides, myricetin 7-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1) and myricetin 7-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (2), together with the known compounds quercetin 3-O-beta-D-glucopyranoside (3), quercetin 3-O-alpha-L-rhamnopyranoside (4), quercetin 3-O-beta-D-galactopyranoside (5), methyl gallate (6), isovanillin (7), 4-hydroxymethylbenzoate (8), 3,4-dihydroxymethylbenzoate (9), and caffeoyl aldehyde (10) were isolated from the leaves of Tachigalia paniculata. The structures of these compounds were determined by spectroscopic methods. Their antioxidant activity was determined by measuring free-radical scavenging effects using three different assays, namely, the Trolox Equivalent Antioxidant Capacity (TEAC) assay, the coupled oxidation of beta-carotene and linoleic acid (autoxidation assay), and the inhibition of xanthine oxidase activity. Compounds 1, 2, and 6 showed activity in the TEAC test, compounds 5-7 and 10 were moderately active in the autoxidation assay, while compounds 1 and 2 were the most potent of the isolates in the xanthine oxidase test.

Authors+Show Affiliations

Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA), Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12444671

Citation

Cioffi, Giuseppina, et al. "Antioxidant and Free-radical Scavenging Activity of Constituents of the Leaves of Tachigalia Paniculata." Journal of Natural Products, vol. 65, no. 11, 2002, pp. 1526-9.
Cioffi G, D'Auria M, Braca A, et al. Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. J Nat Prod. 2002;65(11):1526-9.
Cioffi, G., D'Auria, M., Braca, A., Mendez, J., Castillo, A., Morelli, I., De Simone, F., & De Tommasi, N. (2002). Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. Journal of Natural Products, 65(11), 1526-9.
Cioffi G, et al. Antioxidant and Free-radical Scavenging Activity of Constituents of the Leaves of Tachigalia Paniculata. J Nat Prod. 2002;65(11):1526-9. PubMed PMID: 12444671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. AU - Cioffi,Giuseppina, AU - D'Auria,Marta, AU - Braca,Alessandra, AU - Mendez,Jeannette, AU - Castillo,Anibal, AU - Morelli,Ivano, AU - De Simone,Francesco, AU - De Tommasi,Nunziatina, PY - 2002/11/26/pubmed PY - 2003/3/12/medline PY - 2002/11/26/entrez SP - 1526 EP - 9 JF - Journal of natural products JO - J Nat Prod VL - 65 IS - 11 N2 - Two new myricetin glycosides, myricetin 7-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1) and myricetin 7-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (2), together with the known compounds quercetin 3-O-beta-D-glucopyranoside (3), quercetin 3-O-alpha-L-rhamnopyranoside (4), quercetin 3-O-beta-D-galactopyranoside (5), methyl gallate (6), isovanillin (7), 4-hydroxymethylbenzoate (8), 3,4-dihydroxymethylbenzoate (9), and caffeoyl aldehyde (10) were isolated from the leaves of Tachigalia paniculata. The structures of these compounds were determined by spectroscopic methods. Their antioxidant activity was determined by measuring free-radical scavenging effects using three different assays, namely, the Trolox Equivalent Antioxidant Capacity (TEAC) assay, the coupled oxidation of beta-carotene and linoleic acid (autoxidation assay), and the inhibition of xanthine oxidase activity. Compounds 1, 2, and 6 showed activity in the TEAC test, compounds 5-7 and 10 were moderately active in the autoxidation assay, while compounds 1 and 2 were the most potent of the isolates in the xanthine oxidase test. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/12444671/Antioxidant_and_free_radical_scavenging_activity_of_constituents_of_the_leaves_of_Tachigalia_paniculata_ L2 - https://doi.org/10.1021/np0200764 DB - PRIME DP - Unbound Medicine ER -