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Treatment of dandruff with 5% tea tree oil shampoo.
J Am Acad Dermatol. 2002 Dec; 47(6):852-5.JA

Abstract

BACKGROUND

Dandruff appears to be related to the yeast Pityrosporum ovale. Tea tree oil has antifungal properties with activity against P ovale and may be useful in the treatment of dandruff.

OBJECTIVE

We conducted a randomized, single-blind, parallel-group study to investigate the efficacy and tolerability of 5% tea tree oil and placebo in patients with mild to moderate dandruff.

METHODS

One hundred twenty-six male and female patients, aged 14 years and older, were randomly assigned to receive either 5% tea tree oil shampoo or placebo, which was used daily for 4 weeks. The dandruff was scored on a quadrant-area-severity scale and by patient self-assessment scores of scaliness, itchiness, and greasiness.

RESULTS

The 5% tea tree oil shampoo group showed a 41% improvement in the quadrant-area-severity score compared with 11% in the placebo group (P <.001). Statistically significant improvements were also observed in the total area of involvement score, the total severity score, and the itchiness and greasiness components of the patients' self-assessments. The scaliness component of patient self-assessment improved but was not statistically significant. There were no adverse effects.

CONCLUSION

Five percent tea tree oil appears to effective and well tolerated in the treatment of dandruff.

Authors+Show Affiliations

Satchell AC
Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Saurajen A
No affiliation info available
Bell C
No affiliation info available
Barnetson RS
No affiliation info available

MeSH

Administration, TopicalAdultDermatitis, SeborrheicFemaleFollow-Up StudiesHair PreparationsHumansMaleMiddle AgedProbabilityReference ValuesScalp DermatosesSingle-Blind MethodTea Tree OilTreatment Outcome

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12451368

Citation

Satchell, Andrew C., et al. "Treatment of Dandruff With 5% Tea Tree Oil Shampoo." Journal of the American Academy of Dermatology, vol. 47, no. 6, 2002, pp. 852-5.
Satchell AC, Saurajen A, Bell C, et al. Treatment of dandruff with 5% tea tree oil shampoo. J Am Acad Dermatol. 2002;47(6):852-5.
Satchell, A. C., Saurajen, A., Bell, C., & Barnetson, R. S. (2002). Treatment of dandruff with 5% tea tree oil shampoo. Journal of the American Academy of Dermatology, 47(6), 852-5.
Satchell AC, et al. Treatment of Dandruff With 5% Tea Tree Oil Shampoo. J Am Acad Dermatol. 2002;47(6):852-5. PubMed PMID: 12451368.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of dandruff with 5% tea tree oil shampoo. AU - Satchell,Andrew C, AU - Saurajen,Anne, AU - Bell,Craig, AU - Barnetson,Ross StC, PY - 2002/11/27/pubmed PY - 2003/1/10/medline PY - 2002/11/27/entrez SP - 852 EP - 5 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 47 IS - 6 N2 - BACKGROUND: Dandruff appears to be related to the yeast Pityrosporum ovale. Tea tree oil has antifungal properties with activity against P ovale and may be useful in the treatment of dandruff. OBJECTIVE: We conducted a randomized, single-blind, parallel-group study to investigate the efficacy and tolerability of 5% tea tree oil and placebo in patients with mild to moderate dandruff. METHODS: One hundred twenty-six male and female patients, aged 14 years and older, were randomly assigned to receive either 5% tea tree oil shampoo or placebo, which was used daily for 4 weeks. The dandruff was scored on a quadrant-area-severity scale and by patient self-assessment scores of scaliness, itchiness, and greasiness. RESULTS: The 5% tea tree oil shampoo group showed a 41% improvement in the quadrant-area-severity score compared with 11% in the placebo group (P <.001). Statistically significant improvements were also observed in the total area of involvement score, the total severity score, and the itchiness and greasiness components of the patients' self-assessments. The scaliness component of patient self-assessment improved but was not statistically significant. There were no adverse effects. CONCLUSION: Five percent tea tree oil appears to effective and well tolerated in the treatment of dandruff. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/12451368/Treatment_of_dandruff_with_5_tea_tree_oil_shampoo_ DB - PRIME DP - Unbound Medicine ER -