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[Electrical impedance scanning in the differentiation of suspicious breast lesions: comparison with mammography, ultrasound and histopathology].
Rofo. 2002 Dec; 174(12):1522-9.ROFO

Abstract

PURPOSE

To assess the value of Electrical Impedance Scanning (EIS) in the differentiation of suspicious breast lesions in comparison to mammography (MG) and ultrasound (US).

METHODS

In 95 female patients (median 53.1 ys) 95 suspicious breast lesions (BI-RADS TM III - V) in MG or US underwent targeted EIS (TransScan TS 2000(R); TransScan Medical, Israel; Siemens Elema, Sweden). Histopathologic proof (vacuum-assisted biopsy or surgical biopsy) was obtained in all cases. MG, US and EIS were independently assessed by two radiologists in consensus. Chi-square tests as well as variance-analysis for ROC-statistics were performed.

RESULTS

Of 95 lesions, 44 were benign, 51 malignant. Sensitivity, specificity, positive and negative predictive values were, respectively for MG 95.3 %, 23.5 %, 51.3 % and 85.7 %, for US 86.5 %, 44.2 %, 57.1 % and 79.1 %, for EIS 77.3 %, 82.3 %, 79.1 % and 80.8 %. The ROC-analysis revealed a significant greater area under the curve for EIS than for MG and US. The sensitivity for EIS was higher in lesions < 10 mm (n = 26; 100 %) and in invasive cancers (n = 31; 80.6 %). The negative predictive value of EIS was higher in BI-RADS TM-IV-lesions (83.9 %) as well as in dense breast parenchyma on the mammogram (86.7 %).

CONCLUSION

EIS shows potential adjunctive value to MG and US in the differentiation of suspicious breast lesions.

Authors+Show Affiliations

Universitätsklinik für Radiodiagnostik, Universität Wien, Germany. Michael-fuchsjaeger@univie.ac.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

ger

PubMed ID

12471524

Citation

Fuchsjäger, M H., et al. "[Electrical Impedance Scanning in the Differentiation of Suspicious Breast Lesions: Comparison With Mammography, Ultrasound and Histopathology]." RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, vol. 174, no. 12, 2002, pp. 1522-9.
Fuchsjäger MH, Helbich TH, Ringl H, et al. [Electrical impedance scanning in the differentiation of suspicious breast lesions: comparison with mammography, ultrasound and histopathology]. Rofo. 2002;174(12):1522-9.
Fuchsjäger, M. H., Helbich, T. H., Ringl, H., Funovics, M. A., Rudas, M., Riedl, C., & Pfarl, G. (2002). [Electrical impedance scanning in the differentiation of suspicious breast lesions: comparison with mammography, ultrasound and histopathology]. RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, 174(12), 1522-9.
Fuchsjäger MH, et al. [Electrical Impedance Scanning in the Differentiation of Suspicious Breast Lesions: Comparison With Mammography, Ultrasound and Histopathology]. Rofo. 2002;174(12):1522-9. PubMed PMID: 12471524.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Electrical impedance scanning in the differentiation of suspicious breast lesions: comparison with mammography, ultrasound and histopathology]. AU - Fuchsjäger,M H, AU - Helbich,T H, AU - Ringl,H, AU - Funovics,M A, AU - Rudas,M, AU - Riedl,C, AU - Pfarl,G, PY - 2002/12/10/pubmed PY - 2003/2/1/medline PY - 2002/12/10/entrez SP - 1522 EP - 9 JF - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin JO - Rofo VL - 174 IS - 12 N2 - PURPOSE: To assess the value of Electrical Impedance Scanning (EIS) in the differentiation of suspicious breast lesions in comparison to mammography (MG) and ultrasound (US). METHODS: In 95 female patients (median 53.1 ys) 95 suspicious breast lesions (BI-RADS TM III - V) in MG or US underwent targeted EIS (TransScan TS 2000(R); TransScan Medical, Israel; Siemens Elema, Sweden). Histopathologic proof (vacuum-assisted biopsy or surgical biopsy) was obtained in all cases. MG, US and EIS were independently assessed by two radiologists in consensus. Chi-square tests as well as variance-analysis for ROC-statistics were performed. RESULTS: Of 95 lesions, 44 were benign, 51 malignant. Sensitivity, specificity, positive and negative predictive values were, respectively for MG 95.3 %, 23.5 %, 51.3 % and 85.7 %, for US 86.5 %, 44.2 %, 57.1 % and 79.1 %, for EIS 77.3 %, 82.3 %, 79.1 % and 80.8 %. The ROC-analysis revealed a significant greater area under the curve for EIS than for MG and US. The sensitivity for EIS was higher in lesions < 10 mm (n = 26; 100 %) and in invasive cancers (n = 31; 80.6 %). The negative predictive value of EIS was higher in BI-RADS TM-IV-lesions (83.9 %) as well as in dense breast parenchyma on the mammogram (86.7 %). CONCLUSION: EIS shows potential adjunctive value to MG and US in the differentiation of suspicious breast lesions. SN - 1438-9029 UR - https://www.unboundmedicine.com/medline/citation/12471524/[Electrical_impedance_scanning_in_the_differentiation_of_suspicious_breast_lesions:_comparison_with_mammography_ultrasound_and_histopathology]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2002-35941 DB - PRIME DP - Unbound Medicine ER -