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Prevalence of rectal hypersensitivity in patients with irritable bowel syndrome and its clinical subgroups.
Rev Esp Enferm Dig 2002; 94(5):247-58RE

Abstract

AIM

To evaluate the prevalence of rectal hypersensitivity in our irritable bowel syndrome (IBS) patients, the relationship of hypersensitivity to rectal distensibility and the differences in sensitivity among clinical subgroups of IBS.

MATERIAL AND METHODS

18 healthy subjects and 56 IBS patients (Rome-II criteria; 22 diarrhea-predominant, 15 constipation-predominant and 19 alternating). Rectal sensitivity and distensibility were studied by isobaric phasic distension of a poliethilene bag with a barostat.

RESULTS

IBS patients showed a lower threshold for discomfort, pain and maximum tolerate distension, without any differences in rectal distensibility. 64% of IBS patients were hypersensitive. 89% of patients with alternating IBS were hypersensitive while only 68% and 26% of patients with diarrhea-predominant IBS and constipation-predominant IBS, respectively, were. There were no differences in rectal distensibility between hypersensitive and normosensitive patients.

CONCLUSION

64% of our IBS patients show rectal hypersensitivity, apparently not related to rectal distensibility. Hypersensitivity is mostly found in alternating IBS patients, and rare in constipation-predominant IBS.

Authors+Show Affiliations

Digestive Service, Hospital Clínico San Carlos, Madrid, Spain. ENRIQUE.REY@erey.netNo affiliation info available

Pub Type(s)

Journal Article

Language

eng spa

PubMed ID

12474333

Citation

Rey, E, and M Díaz-Rubio. "Prevalence of Rectal Hypersensitivity in Patients With Irritable Bowel Syndrome and Its Clinical Subgroups." Revista Espanola De Enfermedades Digestivas : Organo Oficial De La Sociedad Espanola De Patologia Digestiva, vol. 94, no. 5, 2002, pp. 247-58.
Rey E, Díaz-Rubio M. Prevalence of rectal hypersensitivity in patients with irritable bowel syndrome and its clinical subgroups. Rev Esp Enferm Dig. 2002;94(5):247-58.
Rey, E., & Díaz-Rubio, M. (2002). Prevalence of rectal hypersensitivity in patients with irritable bowel syndrome and its clinical subgroups. Revista Espanola De Enfermedades Digestivas : Organo Oficial De La Sociedad Espanola De Patologia Digestiva, 94(5), pp. 247-58.
Rey E, Díaz-Rubio M. Prevalence of Rectal Hypersensitivity in Patients With Irritable Bowel Syndrome and Its Clinical Subgroups. Rev Esp Enferm Dig. 2002;94(5):247-58. PubMed PMID: 12474333.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of rectal hypersensitivity in patients with irritable bowel syndrome and its clinical subgroups. AU - Rey,E, AU - Díaz-Rubio,M, PY - 2002/12/12/pubmed PY - 2003/5/31/medline PY - 2002/12/12/entrez SP - 247 EP - 58 JF - Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva JO - Rev Esp Enferm Dig VL - 94 IS - 5 N2 - AIM: To evaluate the prevalence of rectal hypersensitivity in our irritable bowel syndrome (IBS) patients, the relationship of hypersensitivity to rectal distensibility and the differences in sensitivity among clinical subgroups of IBS. MATERIAL AND METHODS: 18 healthy subjects and 56 IBS patients (Rome-II criteria; 22 diarrhea-predominant, 15 constipation-predominant and 19 alternating). Rectal sensitivity and distensibility were studied by isobaric phasic distension of a poliethilene bag with a barostat. RESULTS: IBS patients showed a lower threshold for discomfort, pain and maximum tolerate distension, without any differences in rectal distensibility. 64% of IBS patients were hypersensitive. 89% of patients with alternating IBS were hypersensitive while only 68% and 26% of patients with diarrhea-predominant IBS and constipation-predominant IBS, respectively, were. There were no differences in rectal distensibility between hypersensitive and normosensitive patients. CONCLUSION: 64% of our IBS patients show rectal hypersensitivity, apparently not related to rectal distensibility. Hypersensitivity is mostly found in alternating IBS patients, and rare in constipation-predominant IBS. SN - 1130-0108 UR - https://www.unboundmedicine.com/medline/citation/12474333/Prevalence_of_rectal_hypersensitivity_in_patients_with_irritable_bowel_syndrome_and_its_clinical_subgroups_ L2 - http://www.diseaseinfosearch.org/result/3876 DB - PRIME DP - Unbound Medicine ER -