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[Nutrition and health--fish fatty acids against fatal coronary heart disease].
Ned Tijdschr Geneeskd. 2002 Nov 23; 146(47):2229-33.NT

Abstract

There are strong indications that eating (fatty) fish or n-3 fatty acids from fish reduces the risk of fata coronary heart disease (CHD). Observational studies in the general population show that consumption of moderate amounts of fish or n-3 fatty acids from fish are associated with a lower risk of fatal coronary heart disease and in particular sudden cardiac death. The most plausible hypothesis is that n-3 fatty acids reduce the risk of CHD mortality via anti-arrhythmic effects. Two clinical intervention trials show that prescription of fish or n-3 fatty acids to patients with prior myocardial infarction is effective in preventing mortality due to CHD. Ongoing trials will have to prove the effectiveness of a low dose of n-3 fatty acids and show that the underlying mechanism involves a protective effect against life-threatening arrhythmias. In addition to other recommendations for a healthier diet and lifestyle, consumption of one or two fatty fish meals a week is a highly effective and safe measure to reduce CHD mortality in both the general population and patients.

Authors+Show Affiliations

Wageningen Universiteit, Wageningen Centre for Food Sciences (WCFS) en afd. Humane Voeding en Epidemiologie, Bomenweg 2, 6703 HD Wageningen. peter.zock@wur.nlNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

dut

PubMed ID

12481519

Citation

Zock, P L., and D Kromhout. "[Nutrition and Health--fish Fatty Acids Against Fatal Coronary Heart Disease]." Nederlands Tijdschrift Voor Geneeskunde, vol. 146, no. 47, 2002, pp. 2229-33.
Zock PL, Kromhout D. [Nutrition and health--fish fatty acids against fatal coronary heart disease]. Ned Tijdschr Geneeskd. 2002;146(47):2229-33.
Zock, P. L., & Kromhout, D. (2002). [Nutrition and health--fish fatty acids against fatal coronary heart disease]. Nederlands Tijdschrift Voor Geneeskunde, 146(47), 2229-33.
Zock PL, Kromhout D. [Nutrition and Health--fish Fatty Acids Against Fatal Coronary Heart Disease]. Ned Tijdschr Geneeskd. 2002 Nov 23;146(47):2229-33. PubMed PMID: 12481519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Nutrition and health--fish fatty acids against fatal coronary heart disease]. AU - Zock,P L, AU - Kromhout,D, PY - 2002/12/17/pubmed PY - 2003/3/5/medline PY - 2002/12/17/entrez SP - 2229 EP - 33 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 146 IS - 47 N2 - There are strong indications that eating (fatty) fish or n-3 fatty acids from fish reduces the risk of fata coronary heart disease (CHD). Observational studies in the general population show that consumption of moderate amounts of fish or n-3 fatty acids from fish are associated with a lower risk of fatal coronary heart disease and in particular sudden cardiac death. The most plausible hypothesis is that n-3 fatty acids reduce the risk of CHD mortality via anti-arrhythmic effects. Two clinical intervention trials show that prescription of fish or n-3 fatty acids to patients with prior myocardial infarction is effective in preventing mortality due to CHD. Ongoing trials will have to prove the effectiveness of a low dose of n-3 fatty acids and show that the underlying mechanism involves a protective effect against life-threatening arrhythmias. In addition to other recommendations for a healthier diet and lifestyle, consumption of one or two fatty fish meals a week is a highly effective and safe measure to reduce CHD mortality in both the general population and patients. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/12481519/[Nutrition_and_health__fish_fatty_acids_against_fatal_coronary_heart_disease]_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -