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Carboxyhaemoglobin dissociation in the cadaver following attempted resuscitation.
J Clin Pathol. 1976 Jan; 29(1):27-9.JC

Abstract

A series of 300 cases of fatal carbon-monoxide poisoning showed wide variations in carboxyhaemoglobin saturation. Levels below 50% in 24 subjects under the age of 70 were probably falsely low following attempted resuscitation on the way to hospital. Artificial respiration, especially with oxygen-rich gas, causes dissociation of carboxyhaemoglobin in the lungs of the cadaver while movement of blood into and out of the lungs, with mixing, lowers the saturation levels in the neighbouring large veins. In four cases subclavian blood showed saturation levels much lower than blood from sites further from the lungs. Blood should be taken from the femoral vein to get true readings.

Authors

No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

1249248

Citation

Rice, H M.. "Carboxyhaemoglobin Dissociation in the Cadaver Following Attempted Resuscitation." Journal of Clinical Pathology, vol. 29, no. 1, 1976, pp. 27-9.
Rice HM. Carboxyhaemoglobin dissociation in the cadaver following attempted resuscitation. J Clin Pathol. 1976;29(1):27-9.
Rice, H. M. (1976). Carboxyhaemoglobin dissociation in the cadaver following attempted resuscitation. Journal of Clinical Pathology, 29(1), 27-9.
Rice HM. Carboxyhaemoglobin Dissociation in the Cadaver Following Attempted Resuscitation. J Clin Pathol. 1976;29(1):27-9. PubMed PMID: 1249248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carboxyhaemoglobin dissociation in the cadaver following attempted resuscitation. A1 - Rice,H M, PY - 1976/1/1/pubmed PY - 1976/1/1/medline PY - 1976/1/1/entrez SP - 27 EP - 9 JF - Journal of clinical pathology JO - J Clin Pathol VL - 29 IS - 1 N2 - A series of 300 cases of fatal carbon-monoxide poisoning showed wide variations in carboxyhaemoglobin saturation. Levels below 50% in 24 subjects under the age of 70 were probably falsely low following attempted resuscitation on the way to hospital. Artificial respiration, especially with oxygen-rich gas, causes dissociation of carboxyhaemoglobin in the lungs of the cadaver while movement of blood into and out of the lungs, with mixing, lowers the saturation levels in the neighbouring large veins. In four cases subclavian blood showed saturation levels much lower than blood from sites further from the lungs. Blood should be taken from the femoral vein to get true readings. SN - 0021-9746 UR - https://www.unboundmedicine.com/medline/citation/1249248/Carboxyhaemoglobin_dissociation_in_the_cadaver_following_attempted_resuscitation_ DB - PRIME DP - Unbound Medicine ER -