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Behavioral naltrexone therapy: an integrated treatment for opiate dependence.
J Subst Abuse Treat. 2002 Dec; 23(4):351-60.JS

Abstract

Treatment of opiate dependence with naltrexone has been limited by poor compliance. Behavioral Naltrexone Therapy (BNT) was developed to promote adherence to naltrexone and lifestyle changes supportive of abstinence, by incorporating components from empirically validated treatments, including Network Therapy with a significant other to monitor medication compliance, the Community Reinforcement Approach, and voucher incentives. An overview is presented of the BNT treatment manual. In an uncontrolled Stage I trial (N = 47), 19% completed the 6-month course of treatment. Retention was especially poor in the subsample of patients who were using methadone at baseline (N = 18; 39% completed 1 month, none completed 6 months), and more encouraging among heroin-dependent patients (N = 29; 65% completed 1 month, 31% completed 6 months). Thus, attrition continues to be a serious problem for naltrexone maintenance, although further efforts to develop interventions such as BNT are warranted.

Authors+Show Affiliations

The New York State Psychiatric Institute, Division on Substance Abuse, Substance Treatment and Research Service, 1051 Riverside Drive, New York, NY 10032, USA. rothenb@pi.cpmc.columbia.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

12495797

Citation

Rothenberg, Jami L., et al. "Behavioral Naltrexone Therapy: an Integrated Treatment for Opiate Dependence." Journal of Substance Abuse Treatment, vol. 23, no. 4, 2002, pp. 351-60.
Rothenberg JL, Sullivan MA, Church SH, et al. Behavioral naltrexone therapy: an integrated treatment for opiate dependence. J Subst Abuse Treat. 2002;23(4):351-60.
Rothenberg, J. L., Sullivan, M. A., Church, S. H., Seracini, A., Collins, E., Kleber, H. D., & Nunes, E. V. (2002). Behavioral naltrexone therapy: an integrated treatment for opiate dependence. Journal of Substance Abuse Treatment, 23(4), 351-60.
Rothenberg JL, et al. Behavioral Naltrexone Therapy: an Integrated Treatment for Opiate Dependence. J Subst Abuse Treat. 2002;23(4):351-60. PubMed PMID: 12495797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Behavioral naltrexone therapy: an integrated treatment for opiate dependence. AU - Rothenberg,Jami L, AU - Sullivan,Maria A, AU - Church,Sarah H, AU - Seracini,Angela, AU - Collins,Eric, AU - Kleber,Herbert D, AU - Nunes,Edward V, PY - 2002/12/24/pubmed PY - 2003/6/24/medline PY - 2002/12/24/entrez SP - 351 EP - 60 JF - Journal of substance abuse treatment JO - J Subst Abuse Treat VL - 23 IS - 4 N2 - Treatment of opiate dependence with naltrexone has been limited by poor compliance. Behavioral Naltrexone Therapy (BNT) was developed to promote adherence to naltrexone and lifestyle changes supportive of abstinence, by incorporating components from empirically validated treatments, including Network Therapy with a significant other to monitor medication compliance, the Community Reinforcement Approach, and voucher incentives. An overview is presented of the BNT treatment manual. In an uncontrolled Stage I trial (N = 47), 19% completed the 6-month course of treatment. Retention was especially poor in the subsample of patients who were using methadone at baseline (N = 18; 39% completed 1 month, none completed 6 months), and more encouraging among heroin-dependent patients (N = 29; 65% completed 1 month, 31% completed 6 months). Thus, attrition continues to be a serious problem for naltrexone maintenance, although further efforts to develop interventions such as BNT are warranted. SN - 0740-5472 UR - https://www.unboundmedicine.com/medline/citation/12495797/Behavioral_naltrexone_therapy:_an_integrated_treatment_for_opiate_dependence_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S074054720200301X DB - PRIME DP - Unbound Medicine ER -