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In vitro antimicrobial activity of ethanol and water extracts of Cassia alata.
J Ethnopharmacol. 2003 Jan; 84(1):1-4.JE

Abstract

Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. The degree of susceptibility varied, the water extract from barks showed bigger inhibition zone than the ethanol extracts (12-16 and 10-14 mm, diameter respectively). The growth of Aspergillus fumigatus and Microsporum canis were not affected by all types of the plant extracts. Results were comparable to standard antifungal drug Tioconazole (18 mm diameter) at equivalent concentration. The anti-bacterial activity of C. alata extracts on S. aureus was detected with only the leaves extracts using water and ethanol. The water extract exhibited higher antibacterial activity than the ethanol extract from leaves (inhibition zones of 11-14 and 9-11 mm, respectively). E. coli showed resistance to all types of extracts. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms.

Authors+Show Affiliations

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. nhareet@medic.upm.edu.myNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12499068

Citation

Somchit, M N., et al. "In Vitro Antimicrobial Activity of Ethanol and Water Extracts of Cassia Alata." Journal of Ethnopharmacology, vol. 84, no. 1, 2003, pp. 1-4.
Somchit MN, Reezal I, Nur IE, et al. In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. J Ethnopharmacol. 2003;84(1):1-4.
Somchit, M. N., Reezal, I., Nur, I. E., & Mutalib, A. R. (2003). In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. Journal of Ethnopharmacology, 84(1), 1-4.
Somchit MN, et al. In Vitro Antimicrobial Activity of Ethanol and Water Extracts of Cassia Alata. J Ethnopharmacol. 2003;84(1):1-4. PubMed PMID: 12499068.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. AU - Somchit,M N, AU - Reezal,I, AU - Nur,I Elysha, AU - Mutalib,A R, PY - 2002/12/25/pubmed PY - 2003/5/20/medline PY - 2002/12/25/entrez SP - 1 EP - 4 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 84 IS - 1 N2 - Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. The degree of susceptibility varied, the water extract from barks showed bigger inhibition zone than the ethanol extracts (12-16 and 10-14 mm, diameter respectively). The growth of Aspergillus fumigatus and Microsporum canis were not affected by all types of the plant extracts. Results were comparable to standard antifungal drug Tioconazole (18 mm diameter) at equivalent concentration. The anti-bacterial activity of C. alata extracts on S. aureus was detected with only the leaves extracts using water and ethanol. The water extract exhibited higher antibacterial activity than the ethanol extract from leaves (inhibition zones of 11-14 and 9-11 mm, respectively). E. coli showed resistance to all types of extracts. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/12499068/In_vitro_antimicrobial_activity_of_ethanol_and_water_extracts_of_Cassia_alata_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378874102001460 DB - PRIME DP - Unbound Medicine ER -