Tags

Type your tag names separated by a space and hit enter

Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects.
Chem Phys Lipids 2002; 121(1-2):35-43CP

Abstract

Over the last few years considerable attention has focused on cannabidiol (CBD), a major non-psychotropic constituent of Cannabis. In Part I of this review we present a condensed survey of the chemistry of CBD; in Part II, to be published later, we shall discuss the anti-convulsive, anti-anxiety, anti-psychotic, anti-nausea and anti-rheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors and its mechanism of action is yet unknown. In Part II we shall also present evidence that it is conceivable that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its anti-oxidative effect.

Authors+Show Affiliations

Department of Medicinal Chemistry and Natural Products, Medical Faculty, Hebrew University of Jerusalem, Ein Kerem Campus, 91120, Jerusalem, Israel. mechou@cc.huji.ac.ilNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12505688

Citation

Mechoulam, Raphael, and Lumír Hanus. "Cannabidiol: an Overview of some Chemical and Pharmacological Aspects. Part I: Chemical Aspects." Chemistry and Physics of Lipids, vol. 121, no. 1-2, 2002, pp. 35-43.
Mechoulam R, Hanus L. Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. Chem Phys Lipids. 2002;121(1-2):35-43.
Mechoulam, R., & Hanus, L. (2002). Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. Chemistry and Physics of Lipids, 121(1-2), pp. 35-43.
Mechoulam R, Hanus L. Cannabidiol: an Overview of some Chemical and Pharmacological Aspects. Part I: Chemical Aspects. Chem Phys Lipids. 2002 Dec 31;121(1-2):35-43. PubMed PMID: 12505688.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. AU - Mechoulam,Raphael, AU - Hanus,Lumír, PY - 2002/12/31/pubmed PY - 2003/8/23/medline PY - 2002/12/31/entrez SP - 35 EP - 43 JF - Chemistry and physics of lipids JO - Chem. Phys. Lipids VL - 121 IS - 1-2 N2 - Over the last few years considerable attention has focused on cannabidiol (CBD), a major non-psychotropic constituent of Cannabis. In Part I of this review we present a condensed survey of the chemistry of CBD; in Part II, to be published later, we shall discuss the anti-convulsive, anti-anxiety, anti-psychotic, anti-nausea and anti-rheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors and its mechanism of action is yet unknown. In Part II we shall also present evidence that it is conceivable that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its anti-oxidative effect. SN - 0009-3084 UR - https://www.unboundmedicine.com/medline/citation/12505688/Cannabidiol:_an_overview_of_some_chemical_and_pharmacological_aspects__Part_I:_chemical_aspects_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0009308402001445 DB - PRIME DP - Unbound Medicine ER -