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Time of onset of uveitis in children with juvenile rheumatoid arthritis.
J AAPOS. 2002 Dec; 6(6):373-6.JA

Abstract

BACKGROUND

Recently, it has been advocated to decrease the frequency of eye examinations to screen for uveitis in children with juvenile rheumatoid arthritis (JRA) because of the low yield of positive findings after an initial normal eye examination. This study was undertaken to determine the time interval for the development of uveitis after the diagnosis of JRA and to further describe patients who develop uveitis related to JRA.

METHODS

This was a retrospective chart review of all patients with JRA examined by either of 2 pediatric ophthalmologists from August 1984 to June 2001. All patients were also under the care of the Pediatric Rheumatology Division at Schneider Children's Hospital. Age of diagnosis of JRA, disease onset subtype of JRA, antinuclear antibody titers, age of diagnosis of uveitis, and complications from uveitis were recorded.

RESULTS

One hundred fifty eight patients with JRA had eye examinations; 39 (25%) developed uveitis. Sixteen patients had uveitis on the initial eye examination, and 23 subsequently developed uveitis. When uveitis was absent at the initial eye examination, the mean time to develop it was 20 months (range, 4-81 months).

CONCLUSIONS

A normal initial eye examination does not preclude the development of uveitis in patients with JRA. We recommend continuing the current standards of ophthalmologic examinations to screen for uveitis in children with JRA as prescribed by the Section on Rheumatology and Ophthalmology of the American Academy of Pediatrics.

Authors+Show Affiliations

Department of Ophthalmology, Long Island Jewish Medical Center and North Shore University Hospital, Great Neck, NY, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

12506279

Citation

Kodsi, Sylvia R., et al. "Time of Onset of Uveitis in Children With Juvenile Rheumatoid Arthritis." Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus, vol. 6, no. 6, 2002, pp. 373-6.
Kodsi SR, Rubin SE, Milojevic D, et al. Time of onset of uveitis in children with juvenile rheumatoid arthritis. J AAPOS. 2002;6(6):373-6.
Kodsi, S. R., Rubin, S. E., Milojevic, D., Ilowite, N., & Gottlieb, B. (2002). Time of onset of uveitis in children with juvenile rheumatoid arthritis. Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus, 6(6), 373-6.
Kodsi SR, et al. Time of Onset of Uveitis in Children With Juvenile Rheumatoid Arthritis. J AAPOS. 2002;6(6):373-6. PubMed PMID: 12506279.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Time of onset of uveitis in children with juvenile rheumatoid arthritis. AU - Kodsi,Sylvia R, AU - Rubin,Steven E, AU - Milojevic,Diana, AU - Ilowite,Norman, AU - Gottlieb,Beth, PY - 2002/12/31/pubmed PY - 2003/2/14/medline PY - 2002/12/31/entrez SP - 373 EP - 6 JF - Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus JO - J AAPOS VL - 6 IS - 6 N2 - BACKGROUND: Recently, it has been advocated to decrease the frequency of eye examinations to screen for uveitis in children with juvenile rheumatoid arthritis (JRA) because of the low yield of positive findings after an initial normal eye examination. This study was undertaken to determine the time interval for the development of uveitis after the diagnosis of JRA and to further describe patients who develop uveitis related to JRA. METHODS: This was a retrospective chart review of all patients with JRA examined by either of 2 pediatric ophthalmologists from August 1984 to June 2001. All patients were also under the care of the Pediatric Rheumatology Division at Schneider Children's Hospital. Age of diagnosis of JRA, disease onset subtype of JRA, antinuclear antibody titers, age of diagnosis of uveitis, and complications from uveitis were recorded. RESULTS: One hundred fifty eight patients with JRA had eye examinations; 39 (25%) developed uveitis. Sixteen patients had uveitis on the initial eye examination, and 23 subsequently developed uveitis. When uveitis was absent at the initial eye examination, the mean time to develop it was 20 months (range, 4-81 months). CONCLUSIONS: A normal initial eye examination does not preclude the development of uveitis in patients with JRA. We recommend continuing the current standards of ophthalmologic examinations to screen for uveitis in children with JRA as prescribed by the Section on Rheumatology and Ophthalmology of the American Academy of Pediatrics. SN - 1091-8531 UR - https://www.unboundmedicine.com/medline/citation/12506279/Time_of_onset_of_uveitis_in_children_with_juvenile_rheumatoid_arthritis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1091853102000940 DB - PRIME DP - Unbound Medicine ER -