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[Studies on chemical constituents in the root of Desmos grandifolius (I)].
Zhongguo Zhong Yao Za Zhi. 2000 Jul; 25(7):419-21.ZZ

Abstract

OBJECTIVE

To investigate new compounds with anti-tumor activities from the root of Desmos grandifolius of Annonaceae.

METHOD

The chemical constituents were isolated by silica gel column chromatography, and the structures were elucidated by UV, IR, MS, 1H NMR, 13C NMR, H-H COSY and NOESY analysis.

RESULTS

Six compounds have been isolated from the CHCl3 extract of this plant and identified as lawinal(I), isolawinal(II), desmethoxymatteucinol(III), benzoic acid(IV), beta-sitosterol(V) and sitgmasterol (VI).

CONCLUSION

All compounds were found from this plant for the first time. Three dihydroflavonoids isolated from this species are characterized by A-ring substitution and no B-ring substitution.

Authors+Show Affiliations

Hospital 306 of PLA, Beijing 100101, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

12515223

Citation

Wu, J H., et al. "[Studies On Chemical Constituents in the Root of Desmos Grandifolius (I)]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 25, no. 7, 2000, pp. 419-21.
Wu JH, Mao SL, Liao SX, et al. [Studies on chemical constituents in the root of Desmos grandifolius (I)]. Zhongguo Zhong Yao Za Zhi. 2000;25(7):419-21.
Wu, J. H., Mao, S. L., Liao, S. X., Shi, W. H., Su, Z. W., & Lan, C. Q. (2000). [Studies on chemical constituents in the root of Desmos grandifolius (I)]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 25(7), 419-21.
Wu JH, et al. [Studies On Chemical Constituents in the Root of Desmos Grandifolius (I)]. Zhongguo Zhong Yao Za Zhi. 2000;25(7):419-21. PubMed PMID: 12515223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on chemical constituents in the root of Desmos grandifolius (I)]. AU - Wu,J H, AU - Mao,S L, AU - Liao,S X, AU - Shi,W H, AU - Su,Z W, AU - Lan,C Q, PY - 2003/1/8/pubmed PY - 2003/3/19/medline PY - 2003/1/8/entrez SP - 419 EP - 21 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 25 IS - 7 N2 - OBJECTIVE: To investigate new compounds with anti-tumor activities from the root of Desmos grandifolius of Annonaceae. METHOD: The chemical constituents were isolated by silica gel column chromatography, and the structures were elucidated by UV, IR, MS, 1H NMR, 13C NMR, H-H COSY and NOESY analysis. RESULTS: Six compounds have been isolated from the CHCl3 extract of this plant and identified as lawinal(I), isolawinal(II), desmethoxymatteucinol(III), benzoic acid(IV), beta-sitosterol(V) and sitgmasterol (VI). CONCLUSION: All compounds were found from this plant for the first time. Three dihydroflavonoids isolated from this species are characterized by A-ring substitution and no B-ring substitution. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/12515223/[Studies_on_chemical_constituents_in_the_root_of_Desmos_grandifolius__I_]_ DB - PRIME DP - Unbound Medicine ER -
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