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[Genetic studies of 13 loci in Guangdong Han population by two multiplex PCR systems and its forensic application].
Fa Yi Xue Za Zhi. 2001 May; 17(2):82-5.FY

Abstract

OBJECTIVE

The genetic studies of 13 short tandem repeats(STRs) loci in two multiplex amplification systems were carried out on Chinese Han population in Guangdong.

METHODS

DNA samples from 328 unrelated individuals were screened. The 13 loci were D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, D16S539, TH01, TPOX and CSF1PO. The PCR products were analyzed and genotyped by ABI 377-96 Sequencer.

RESULTS

The combined power of discrimination (DP) was 0.999999999999993 and the combined paternity of exclusion(PE) was 99.999%. These 13 loci met the Hardy-Weinberg expectations.

CONCLUSION

The two multiplex amplification systems were very useful in forensic case investigation.

Authors+Show Affiliations

Li Y
Guangzhou Criminal Science & Technology Institute, Guangzhou 510030.
Wang SB
No affiliation info available
Liu C
No affiliation info available
Li HX
No affiliation info available
Hu HY
No affiliation info available
Liu H
No affiliation info available
Liu CH
No affiliation info available
Chen XH
No affiliation info available

MeSH

Asian PeopleChinaFemaleGene FrequencyGenetics, PopulationHumansMalePaternityPolymerase Chain ReactionPolymorphism, GeneticTandem Repeat Sequences

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

12533862

Citation

Li, Y, et al. "[Genetic Studies of 13 Loci in Guangdong Han Population By Two Multiplex PCR Systems and Its Forensic Application]." Fa Yi Xue Za Zhi, vol. 17, no. 2, 2001, pp. 82-5.
Li Y, Wang SB, Liu C, et al. [Genetic studies of 13 loci in Guangdong Han population by two multiplex PCR systems and its forensic application]. Fa Yi Xue Za Zhi. 2001;17(2):82-5.
Li, Y., Wang, S. B., Liu, C., Li, H. X., Hu, H. Y., Liu, H., Liu, C. H., & Chen, X. H. (2001). [Genetic studies of 13 loci in Guangdong Han population by two multiplex PCR systems and its forensic application]. Fa Yi Xue Za Zhi, 17(2), 82-5.
Li Y, et al. [Genetic Studies of 13 Loci in Guangdong Han Population By Two Multiplex PCR Systems and Its Forensic Application]. Fa Yi Xue Za Zhi. 2001;17(2):82-5. PubMed PMID: 12533862.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Genetic studies of 13 loci in Guangdong Han population by two multiplex PCR systems and its forensic application]. AU - Li,Y, AU - Wang,S B, AU - Liu,C, AU - Li,H X, AU - Hu,H Y, AU - Liu,H, AU - Liu,C H, AU - Chen,X H, PY - 2003/1/22/pubmed PY - 2003/4/5/medline PY - 2003/1/22/entrez SP - 82 EP - 5 JF - Fa yi xue za zhi JO - Fa Yi Xue Za Zhi VL - 17 IS - 2 N2 - OBJECTIVE: The genetic studies of 13 short tandem repeats(STRs) loci in two multiplex amplification systems were carried out on Chinese Han population in Guangdong. METHODS: DNA samples from 328 unrelated individuals were screened. The 13 loci were D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, D16S539, TH01, TPOX and CSF1PO. The PCR products were analyzed and genotyped by ABI 377-96 Sequencer. RESULTS: The combined power of discrimination (DP) was 0.999999999999993 and the combined paternity of exclusion(PE) was 99.999%. These 13 loci met the Hardy-Weinberg expectations. CONCLUSION: The two multiplex amplification systems were very useful in forensic case investigation. SN - 1004-5619 UR - https://www.unboundmedicine.com/medline/citation/12533862/[Genetic_studies_of_13_loci_in_Guangdong_Han_population_by_two_multiplex_PCR_systems_and_its_forensic_application]_ DB - PRIME DP - Unbound Medicine ER -