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[Nutrition and health--favorable effect of wine and wine flavonoids on cardiovascular diseases].
Ned Tijdschr Geneeskd. 2002 Dec 21; 146(51):2466-9.NT

Abstract

Epidemiological studies have shown a favourable effect of moderate alcohol consumption with regard to atherosclerotic disorders. In addition to alcohol, wine contains a large number of other components including polyphenols. These polyphenols mainly originate from the skins and seeds of grapes and, because of differences in vinification, their variety and concentration is higher in red wine than in white wine. In vitro and ex vivo studies have shown that some of these polyphenols are able to slow down LDL-cholesterol oxidation, stimulate NO production, influence prostaglandin synthesis and inhibit platelet aggregation. However, little is known about their resorption, bioavailability and effectiveness in vivo. Since data from intervention studies with wine polyphenols are also lacking, no statement can yet be made about any clinically relevant effect of these components, in either red or white wine, in terms of cardiovascular diseases.

Authors+Show Affiliations

Meander Medisch Centrum, afd. Interne Geneeskunde, Postbus 1502, 3800 BM Amersfoort. a.wiel@meandermc.nl

Pub Type(s)

English Abstract
Journal Article
Review

Language

dut

PubMed ID

12534098

Citation

van de Wiel, A. "[Nutrition and Health--favorable Effect of Wine and Wine Flavonoids On Cardiovascular Diseases]." Nederlands Tijdschrift Voor Geneeskunde, vol. 146, no. 51, 2002, pp. 2466-9.
van de Wiel A. [Nutrition and health--favorable effect of wine and wine flavonoids on cardiovascular diseases]. Ned Tijdschr Geneeskd. 2002;146(51):2466-9.
van de Wiel, A. (2002). [Nutrition and health--favorable effect of wine and wine flavonoids on cardiovascular diseases]. Nederlands Tijdschrift Voor Geneeskunde, 146(51), 2466-9.
van de Wiel A. [Nutrition and Health--favorable Effect of Wine and Wine Flavonoids On Cardiovascular Diseases]. Ned Tijdschr Geneeskd. 2002 Dec 21;146(51):2466-9. PubMed PMID: 12534098.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Nutrition and health--favorable effect of wine and wine flavonoids on cardiovascular diseases]. A1 - van de Wiel,A, PY - 2003/1/22/pubmed PY - 2003/4/5/medline PY - 2003/1/22/entrez SP - 2466 EP - 9 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 146 IS - 51 N2 - Epidemiological studies have shown a favourable effect of moderate alcohol consumption with regard to atherosclerotic disorders. In addition to alcohol, wine contains a large number of other components including polyphenols. These polyphenols mainly originate from the skins and seeds of grapes and, because of differences in vinification, their variety and concentration is higher in red wine than in white wine. In vitro and ex vivo studies have shown that some of these polyphenols are able to slow down LDL-cholesterol oxidation, stimulate NO production, influence prostaglandin synthesis and inhibit platelet aggregation. However, little is known about their resorption, bioavailability and effectiveness in vivo. Since data from intervention studies with wine polyphenols are also lacking, no statement can yet be made about any clinically relevant effect of these components, in either red or white wine, in terms of cardiovascular diseases. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/12534098/[Nutrition_and_health__favorable_effect_of_wine_and_wine_flavonoids_on_cardiovascular_diseases]_ L2 - https://www.lens.org/lens/search?q=citation_id:12534098 DB - PRIME DP - Unbound Medicine ER -