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MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer.
AJR Am J Roentgenol. 2003 Feb; 180(2):333-41.AA

Abstract

OBJECTIVE

The purpose of this study was to determine the frequency and positive predictive value of biopsy performed on the basis of MR imaging findings in the contralateral breast in women with recently diagnosed breast cancer.

MATERIALS AND METHODS

We performed a retrospective review of records of 1336 consecutive breast MR imaging examinations over a 2-year period. Of these examinations, 223 imaged the asymptomatic, mammographically normal contralateral breast in women whose breast cancer was diagnosed within 6 months preceding MR imaging. Records of these 223 examinations were reviewed to determine the frequency of recommending contralateral breast biopsy and the biopsy results.

RESULTS

Contralateral breast biopsy was recommended in 72 (32%) of 223 women and performed in 61 women. Cancer occult to mammography and physical examination was detected by MR imaging in 12 women, constituting 20% (12/61) of women who underwent contralateral biopsy and 5% (12/223) of women who underwent contralateral breast MR imaging. Among these 12 cancers, six (50%) were ductal carcinoma in situ (DCIS) and six (50%) were infiltrating carcinoma. The median size of infiltrating carcinoma was 0.5 cm (range, 0.1-1.0 cm). Contralateral biopsy revealed benign (n = 31) or high-risk (n = 18) lesions in 49 women, constituting 80% (49/61) of women who underwent contralateral biopsy and 22% (49/223) of women who underwent contralateral MR imaging.

CONCLUSION

In women with recently diagnosed breast cancer, MR imaging of the contralateral breast led to a biopsy recommendation in 32%. Cancer was found in 20% of women who underwent contralateral breast biopsy and in 5% of women who underwent contralateral breast MR imaging.

Authors+Show Affiliations

Breast Imaging Section, Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12540428

Citation

Liberman, Laura, et al. "MR Imaging Findings in the Contralateral Breast of Women With Recently Diagnosed Breast Cancer." AJR. American Journal of Roentgenology, vol. 180, no. 2, 2003, pp. 333-41.
Liberman L, Morris EA, Kim CM, et al. MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer. AJR Am J Roentgenol. 2003;180(2):333-41.
Liberman, L., Morris, E. A., Kim, C. M., Kaplan, J. B., Abramson, A. F., Menell, J. H., Van Zee, K. J., & Dershaw, D. D. (2003). MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer. AJR. American Journal of Roentgenology, 180(2), 333-41.
Liberman L, et al. MR Imaging Findings in the Contralateral Breast of Women With Recently Diagnosed Breast Cancer. AJR Am J Roentgenol. 2003;180(2):333-41. PubMed PMID: 12540428.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer. AU - Liberman,Laura, AU - Morris,Elizabeth A, AU - Kim,Cathleen M, AU - Kaplan,Jennifer B, AU - Abramson,Andrea F, AU - Menell,Jennifer H, AU - Van Zee,Kimberly J, AU - Dershaw,D David, PY - 2003/1/24/pubmed PY - 2003/2/27/medline PY - 2003/1/24/entrez SP - 333 EP - 41 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 180 IS - 2 N2 - OBJECTIVE: The purpose of this study was to determine the frequency and positive predictive value of biopsy performed on the basis of MR imaging findings in the contralateral breast in women with recently diagnosed breast cancer. MATERIALS AND METHODS: We performed a retrospective review of records of 1336 consecutive breast MR imaging examinations over a 2-year period. Of these examinations, 223 imaged the asymptomatic, mammographically normal contralateral breast in women whose breast cancer was diagnosed within 6 months preceding MR imaging. Records of these 223 examinations were reviewed to determine the frequency of recommending contralateral breast biopsy and the biopsy results. RESULTS: Contralateral breast biopsy was recommended in 72 (32%) of 223 women and performed in 61 women. Cancer occult to mammography and physical examination was detected by MR imaging in 12 women, constituting 20% (12/61) of women who underwent contralateral biopsy and 5% (12/223) of women who underwent contralateral breast MR imaging. Among these 12 cancers, six (50%) were ductal carcinoma in situ (DCIS) and six (50%) were infiltrating carcinoma. The median size of infiltrating carcinoma was 0.5 cm (range, 0.1-1.0 cm). Contralateral biopsy revealed benign (n = 31) or high-risk (n = 18) lesions in 49 women, constituting 80% (49/61) of women who underwent contralateral biopsy and 22% (49/223) of women who underwent contralateral MR imaging. CONCLUSION: In women with recently diagnosed breast cancer, MR imaging of the contralateral breast led to a biopsy recommendation in 32%. Cancer was found in 20% of women who underwent contralateral breast biopsy and in 5% of women who underwent contralateral breast MR imaging. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/12540428/MR_imaging_findings_in_the_contralateral_breast_of_women_with_recently_diagnosed_breast_cancer_ L2 - https://www.ajronline.org/doi/10.2214/ajr.180.2.1800333 DB - PRIME DP - Unbound Medicine ER -