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Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study.
Br Dent J. 2003 Jan 11; 194(1):43-5.BD

Abstract

OBJECTIVE

To assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry.

DESIGN

Prospective clinical trial

SETTING

Department of Sedation, Glasgow Dental Hospital and School, 2001

SUBJECTS AND METHODS

Patients scheduled for oral surgery with conscious sedation. Exclusions included ASA IV -V, inability to use the handset, opioid use and severe respiratory disease.

INTERVENTIONS

Patients were given intravenous propofol to a level of 1.0 microg/ml (reducing from 1.5 microg/ml) using a target controlled infusion system, they then controlled their sedation level by double-clicking a handset which on each activation increased the propofol concentration by 0.2 microg/ml.

MAIN OUTCOME MEASURES

Oxygen saturation, patient satisfaction, and surgeon satisfaction.

RESULTS

Twenty patients were recruited, 16 female and four male. Nineteen patients completed sedation and treatment successfully. Mean lowest oxygen saturation was 94%. No patients were over-sedated. All patients successfully used the system to maintain a level of sedation adequate for their comfort. Patient and surgeon satisfaction were consistently high.

CONCLUSIONS

Initial experience with this novel system has confirmed safety, patient satisfaction and surgeon satisfaction.

Authors+Show Affiliations

Glasgow Dental Hospital and School, Glasgow. leitch@bigfoot.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

12540939

Citation

Leitch, J A., et al. "Patient-maintained Sedation for Oral Surgery Using a Target-controlled Infusion of Propofol - a Pilot Study." British Dental Journal, vol. 194, no. 1, 2003, pp. 43-5.
Leitch JA, Sutcliffe N, Kenny GN. Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study. Br Dent J. 2003;194(1):43-5.
Leitch, J. A., Sutcliffe, N., & Kenny, G. N. (2003). Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study. British Dental Journal, 194(1), 43-5.
Leitch JA, Sutcliffe N, Kenny GN. Patient-maintained Sedation for Oral Surgery Using a Target-controlled Infusion of Propofol - a Pilot Study. Br Dent J. 2003 Jan 11;194(1):43-5. PubMed PMID: 12540939.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study. AU - Leitch,J A, AU - Sutcliffe,N, AU - Kenny,G N C, PY - 2002/03/08/received PY - 2002/09/23/accepted PY - 2003/1/24/pubmed PY - 2003/4/23/medline PY - 2003/1/24/entrez SP - 43 EP - 5 JF - British dental journal JO - Br Dent J VL - 194 IS - 1 N2 - OBJECTIVE: To assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry. DESIGN: Prospective clinical trial SETTING: Department of Sedation, Glasgow Dental Hospital and School, 2001 SUBJECTS AND METHODS: Patients scheduled for oral surgery with conscious sedation. Exclusions included ASA IV -V, inability to use the handset, opioid use and severe respiratory disease. INTERVENTIONS: Patients were given intravenous propofol to a level of 1.0 microg/ml (reducing from 1.5 microg/ml) using a target controlled infusion system, they then controlled their sedation level by double-clicking a handset which on each activation increased the propofol concentration by 0.2 microg/ml. MAIN OUTCOME MEASURES: Oxygen saturation, patient satisfaction, and surgeon satisfaction. RESULTS: Twenty patients were recruited, 16 female and four male. Nineteen patients completed sedation and treatment successfully. Mean lowest oxygen saturation was 94%. No patients were over-sedated. All patients successfully used the system to maintain a level of sedation adequate for their comfort. Patient and surgeon satisfaction were consistently high. CONCLUSIONS: Initial experience with this novel system has confirmed safety, patient satisfaction and surgeon satisfaction. SN - 0007-0610 UR - https://www.unboundmedicine.com/medline/citation/12540939/Patient_maintained_sedation_for_oral_surgery_using_a_target_controlled_infusion_of_propofol___a_pilot_study_ L2 - https://doi.org/10.1038/sj.bdj.4802412 DB - PRIME DP - Unbound Medicine ER -