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[4199 biopsies from the endoscopic normal lower duodenum].
Z Gastroenterol. 2003 Jan; 41(1):69-74.ZG

Abstract

Lower duodenal biopsies (LDB) are not taken at every oesophago-gastro-duodenoscopy (EGD). In the present study, biopsies from the endoscopic normal lower duodenum were checked as a measure of quality assurance. From 1996 to 2000, 9,955 EGD were performed and 4,199 LDB were taken (42.2 %). Of these, 667 showed pathological histology (15.9 %). A non-specific inflammation was seen in 537 cases and lymphangiectasia in 30 cases. Signs of indigenous sprue were described histologically in 6 LDB. In 4 of the 6 first diagnoses, the LDB was taken owing to clinical suspicion of malabsorption syndrome. Giardia lamblia could be detected in 22 patients. Only 6 of the 22 patients had diarrhoea. A total of 18 clinically relevant first diagnoses were made by LDB in asymptomatic patients with normal endoscopic findings in the duodenum. In order to make a relevant first diagnosis, 233 LDB had to be taken. LDB can be dispensed within EGD when there is neither diarrhoea nor loss of weight, and no anemia, iron deficiency, vitamin deficiency, macrocytosis, hypoproteinaemia, meteorism, joint symptoms or fever.

Authors+Show Affiliations

Innere Medizin I, Krankenhaus Bietigheim, Bietighein-Bissingen. walker.innere1@kh-bietigheim.deNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ger

PubMed ID

12541178

Citation

Walker, S, and U Rühl. "[4199 Biopsies From the Endoscopic Normal Lower Duodenum]." Zeitschrift Fur Gastroenterologie, vol. 41, no. 1, 2003, pp. 69-74.
Walker S, Rühl U. [4199 biopsies from the endoscopic normal lower duodenum]. Z Gastroenterol. 2003;41(1):69-74.
Walker, S., & Rühl, U. (2003). [4199 biopsies from the endoscopic normal lower duodenum]. Zeitschrift Fur Gastroenterologie, 41(1), 69-74.
Walker S, Rühl U. [4199 Biopsies From the Endoscopic Normal Lower Duodenum]. Z Gastroenterol. 2003;41(1):69-74. PubMed PMID: 12541178.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [4199 biopsies from the endoscopic normal lower duodenum]. AU - Walker,S, AU - Rühl,U, PY - 2003/1/24/pubmed PY - 2003/4/8/medline PY - 2003/1/24/entrez SP - 69 EP - 74 JF - Zeitschrift fur Gastroenterologie JO - Z Gastroenterol VL - 41 IS - 1 N2 - Lower duodenal biopsies (LDB) are not taken at every oesophago-gastro-duodenoscopy (EGD). In the present study, biopsies from the endoscopic normal lower duodenum were checked as a measure of quality assurance. From 1996 to 2000, 9,955 EGD were performed and 4,199 LDB were taken (42.2 %). Of these, 667 showed pathological histology (15.9 %). A non-specific inflammation was seen in 537 cases and lymphangiectasia in 30 cases. Signs of indigenous sprue were described histologically in 6 LDB. In 4 of the 6 first diagnoses, the LDB was taken owing to clinical suspicion of malabsorption syndrome. Giardia lamblia could be detected in 22 patients. Only 6 of the 22 patients had diarrhoea. A total of 18 clinically relevant first diagnoses were made by LDB in asymptomatic patients with normal endoscopic findings in the duodenum. In order to make a relevant first diagnosis, 233 LDB had to be taken. LDB can be dispensed within EGD when there is neither diarrhoea nor loss of weight, and no anemia, iron deficiency, vitamin deficiency, macrocytosis, hypoproteinaemia, meteorism, joint symptoms or fever. SN - 0044-2771 UR - https://www.unboundmedicine.com/medline/citation/12541178/[4199_biopsies_from_the_endoscopic_normal_lower_duodenum]_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2003-36674 DB - PRIME DP - Unbound Medicine ER -