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[Transcriptional activator PlcR regulate the expression of multiple genes in Bacillus cereus].
Wei Sheng Wu Xue Bao 2001; 41(3):304-9WS

Abstract

Food-poisoning and some diseases of human can be caused by potential pathogenic factors including phospholipases of c-type, hemolysins, enterotoxins, emetic toxin and others from Bacillus cereus which is an opportunistic pathegon. Generally, the expression of pathogenic genes is completed by a co-regulation in many bacteria. The isolation of a mutant, displaying significant reducing expression of lecithinase and general proteolytic activities, from a transposon-induced bank of B. cereus type strain ATCC14579T were described. Sequencing data revealed that a gene with high homology to transcriptional activator (plcR) of B. thuringiensis was inactivated by insertion in this mutant. The results suggest that plcR regulates the expression of multiple genes in B. cereus.

Authors+Show Affiliations

Department of Microbial Science and Technology, Huazhong Agricultural University, Key Laboratory of Agro-Microbiology, Ministry of Agriculture, Wuhan, 430070, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

chi

PubMed ID

12549084

Citation

Wang, L, et al. "[Transcriptional Activator PlcR Regulate the Expression of Multiple Genes in Bacillus Cereus]." Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica, vol. 41, no. 3, 2001, pp. 304-9.
Wang L, Chen Y, Mahillion J, et al. [Transcriptional activator PlcR regulate the expression of multiple genes in Bacillus cereus]. Wei Sheng Wu Xue Bao. 2001;41(3):304-9.
Wang, L., Chen, Y., Mahillion, J., & Yu, Z. (2001). [Transcriptional activator PlcR regulate the expression of multiple genes in Bacillus cereus]. Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica, 41(3), pp. 304-9.
Wang L, et al. [Transcriptional Activator PlcR Regulate the Expression of Multiple Genes in Bacillus Cereus]. Wei Sheng Wu Xue Bao. 2001;41(3):304-9. PubMed PMID: 12549084.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Transcriptional activator PlcR regulate the expression of multiple genes in Bacillus cereus]. AU - Wang,L, AU - Chen,Y, AU - Mahillion,J, AU - Yu,Z, PY - 2003/1/29/pubmed PY - 2004/8/11/medline PY - 2003/1/29/entrez SP - 304 EP - 9 JF - Wei sheng wu xue bao = Acta microbiologica Sinica JO - Wei Sheng Wu Xue Bao VL - 41 IS - 3 N2 - Food-poisoning and some diseases of human can be caused by potential pathogenic factors including phospholipases of c-type, hemolysins, enterotoxins, emetic toxin and others from Bacillus cereus which is an opportunistic pathegon. Generally, the expression of pathogenic genes is completed by a co-regulation in many bacteria. The isolation of a mutant, displaying significant reducing expression of lecithinase and general proteolytic activities, from a transposon-induced bank of B. cereus type strain ATCC14579T were described. Sequencing data revealed that a gene with high homology to transcriptional activator (plcR) of B. thuringiensis was inactivated by insertion in this mutant. The results suggest that plcR regulates the expression of multiple genes in B. cereus. SN - 0001-6209 UR - https://www.unboundmedicine.com/medline/citation/12549084/[Transcriptional_activator_PlcR_regulate_the_expression_of_multiple_genes_in_Bacillus_cereus]_ DB - PRIME DP - Unbound Medicine ER -