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[Studies on risk factors for liver fibrosis of schistosomiasis japonica].

Abstract

OBJECTIVE

To explore the risk factors for schistosomal liver fibrosis.

METHODS

192 hepatitis-negative patients with schistosomiasis were selected and divided into 3 groups according to the result of B ultrasound examination, that is, grade 2 and 3 fibrosis group(81 patients), grade 1 fibrosis group (61 patients) and control group (non-fibrosis, 50 patiets). The univariate and multivariate ordinal regression model was made to analyse the possibly harmful factors influencing the liver damages of these patients.

RESULTS

Four factors were found to be positively associated with schistosomal liver fibrosis. They were: number of treatments of schistosomiasis (OR = 1.75), interval of schistosomal infection(OR = 1.40), history of drinking wine (OR = 1.95) and familial history of advanced schistosomiasis (OR = 2.11).

CONCLUSION

Patients with repeated schistosome infection, long duration of schistosomal infection, long history of drinking and familial history of advanced schistosomiasis had higher risk for liver fibrosis than schistosomiasis patients without these factors.

Authors+Show Affiliations

Department of Epidemiology, Shanghai Medical University, Shanghai 200032.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

12567465

Citation

Liu, Y, et al. "[Studies On Risk Factors for Liver Fibrosis of Schistosomiasis Japonica]." Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases, vol. 18, no. 1, 2000, pp. 18-20.
Liu Y, Yuan HC, Lin DD, et al. [Studies on risk factors for liver fibrosis of schistosomiasis japonica]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2000;18(1):18-20.
Liu, Y., Yuan, H. C., Lin, D. D., Liu, Y. M., Hu, F., Zhao, G. M., Jiang, Q. W., & Zhang, S. J. (2000). [Studies on risk factors for liver fibrosis of schistosomiasis japonica]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases, 18(1), 18-20.
Liu Y, et al. [Studies On Risk Factors for Liver Fibrosis of Schistosomiasis Japonica]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2000;18(1):18-20. PubMed PMID: 12567465.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on risk factors for liver fibrosis of schistosomiasis japonica]. AU - Liu,Y, AU - Yuan,H C, AU - Lin,D D, AU - Liu,Y M, AU - Hu,F, AU - Zhao,G M, AU - Jiang,Q W, AU - Zhang,S J, PY - 2003/2/6/pubmed PY - 2003/9/17/medline PY - 2003/2/6/entrez SP - 18 EP - 20 JF - Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases JO - Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi VL - 18 IS - 1 N2 - OBJECTIVE: To explore the risk factors for schistosomal liver fibrosis. METHODS: 192 hepatitis-negative patients with schistosomiasis were selected and divided into 3 groups according to the result of B ultrasound examination, that is, grade 2 and 3 fibrosis group(81 patients), grade 1 fibrosis group (61 patients) and control group (non-fibrosis, 50 patiets). The univariate and multivariate ordinal regression model was made to analyse the possibly harmful factors influencing the liver damages of these patients. RESULTS: Four factors were found to be positively associated with schistosomal liver fibrosis. They were: number of treatments of schistosomiasis (OR = 1.75), interval of schistosomal infection(OR = 1.40), history of drinking wine (OR = 1.95) and familial history of advanced schistosomiasis (OR = 2.11). CONCLUSION: Patients with repeated schistosome infection, long duration of schistosomal infection, long history of drinking and familial history of advanced schistosomiasis had higher risk for liver fibrosis than schistosomiasis patients without these factors. SN - 1000-7423 UR - https://www.unboundmedicine.com/medline/citation/12567465/[Studies_on_risk_factors_for_liver_fibrosis_of_schistosomiasis_japonica]_ L2 - http://www.diseaseinfosearch.org/result/6440 DB - PRIME DP - Unbound Medicine ER -