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Alcohol and cardiovascular disease--more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease--a review.

Abstract

The effect of average volume of alcohol on coronary heart disease (CHD) is J-shaped in established market economies. Light to moderate drinkers have less risk than abstainers, with heavy drinkers displaying the highest level of risk. This relationship between average volume of alcohol consumption and CHD is modified by different patterns of drinking. Heavy drinking occasions as well as drinking outside meals are related to increased CHD risk, independently of volume of drinking. Beverage type does not seem to have much impact, even though there are some indications that wine is more protective than other forms of alcohol. Physiological mechanisms have been identified to explain this complex relationship between alcohol and CHD. Since patterns of drinking are important in determining CHD risk, they should be included in future epidemiologic studies, together with biomarkers further to test hypotheses about pathways.

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  • Authors+Show Affiliations

    ,

    Addiction Research Institute, Zurich, Switzerland. jtrehm@isf.unizh.ch

    ,

    Source

    Journal of cardiovascular risk 10:1 2003 Feb pg 15-20

    MeSH

    Alcohol Drinking
    Alcoholic Beverages
    Coronary Disease
    Eating
    Humans
    Risk Factors

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    12569232

    Citation

    Rehm, J, et al. "Alcohol and Cardiovascular Disease--more Than One Paradox to Consider. Average Volume of Alcohol Consumption, Patterns of Drinking and Risk of Coronary Heart Disease--a Review." Journal of Cardiovascular Risk, vol. 10, no. 1, 2003, pp. 15-20.
    Rehm J, Sempos CT, Trevisan M. Alcohol and cardiovascular disease--more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease--a review. J Cardiovasc Risk. 2003;10(1):15-20.
    Rehm, J., Sempos, C. T., & Trevisan, M. (2003). Alcohol and cardiovascular disease--more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease--a review. Journal of Cardiovascular Risk, 10(1), pp. 15-20.
    Rehm J, Sempos CT, Trevisan M. Alcohol and Cardiovascular Disease--more Than One Paradox to Consider. Average Volume of Alcohol Consumption, Patterns of Drinking and Risk of Coronary Heart Disease--a Review. J Cardiovasc Risk. 2003;10(1):15-20. PubMed PMID: 12569232.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Alcohol and cardiovascular disease--more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease--a review. AU - Rehm,J, AU - Sempos,C T, AU - Trevisan,M, PY - 2003/2/6/pubmed PY - 2003/6/12/medline PY - 2003/2/6/entrez SP - 15 EP - 20 JF - Journal of cardiovascular risk JO - J Cardiovasc Risk VL - 10 IS - 1 N2 - The effect of average volume of alcohol on coronary heart disease (CHD) is J-shaped in established market economies. Light to moderate drinkers have less risk than abstainers, with heavy drinkers displaying the highest level of risk. This relationship between average volume of alcohol consumption and CHD is modified by different patterns of drinking. Heavy drinking occasions as well as drinking outside meals are related to increased CHD risk, independently of volume of drinking. Beverage type does not seem to have much impact, even though there are some indications that wine is more protective than other forms of alcohol. Physiological mechanisms have been identified to explain this complex relationship between alcohol and CHD. Since patterns of drinking are important in determining CHD risk, they should be included in future epidemiologic studies, together with biomarkers further to test hypotheses about pathways. SN - 1350-6277 UR - https://www.unboundmedicine.com/medline/citation/12569232/Alcohol_and_cardiovascular_disease__more_than_one_paradox_to_consider__Average_volume_of_alcohol_consumption_patterns_of_drinking_and_risk_of_coronary_heart_disease__a_review_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=12569232.ui DB - PRIME DP - Unbound Medicine ER -