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Temba glaucoma study: a population-based cross-sectional survey in urban South Africa.
Ophthalmology 2003; 110(2):376-82O

Abstract

OBJECTIVE

To determine the prevalence and features of glaucoma in an urban South African black population.

DESIGN

Random sampling cross-sectional population survey.

PARTICIPANTS

Black residents of Temba, North West Province, South Africa, age > or =40 years.

MAIN OUTCOME MEASURES

Automated visual field testing and detailed, standardized slit-lamp examination were attempted on all subjects. Glaucoma was diagnosed by use of the scheme proposed by the Working Group for Defining Glaucoma of the International Society of Geographical and Epidemiologic Ophthalmology on the basis of evidence of end-organ damage.

RESULTS

Of 1120 subjects, 839 (74.9%) were examined. The age- and gender-adjusted prevalence of glaucoma of all types was 5.3% (95% confidence interval [CI], 3.9%-7.1%). Primary open-angle glaucoma (POAG) was the most common glaucoma diagnosis, with an adjusted prevalence of 2.9% (95% CI, 1.9%-4.3%). Secondary glaucoma occurred with an adjusted prevalence of 2.0% (95% CI, 1.2%-3.3%). Exfoliative glaucoma was responsible for 16% of all glaucoma cases. The prevalence of primary angle-closure glaucoma was 0.5% (95% CI, 0.13%-1.2%). Of all subjects with glaucoma, 58% were blind in at least one eye. The prevalence of all types of glaucoma increased with age. Of subjects with POAG, 87% had not been previously diagnosed.

CONCLUSIONS

The prevalence of glaucoma in this South African population was higher than that found in white populations, and most cases were undiagnosed and untreated. Glaucoma is a major cause of blindness in this population.

Authors+Show Affiliations

International Centre for Eye Health, the Institute of Ophthalmology, London, United Kingdom. rotchford@supanet.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12578784

Citation

Rotchford, Alan P., et al. "Temba Glaucoma Study: a Population-based Cross-sectional Survey in Urban South Africa." Ophthalmology, vol. 110, no. 2, 2003, pp. 376-82.
Rotchford AP, Kirwan JF, Muller MA, et al. Temba glaucoma study: a population-based cross-sectional survey in urban South Africa. Ophthalmology. 2003;110(2):376-82.
Rotchford, A. P., Kirwan, J. F., Muller, M. A., Johnson, G. J., & Roux, P. (2003). Temba glaucoma study: a population-based cross-sectional survey in urban South Africa. Ophthalmology, 110(2), pp. 376-82.
Rotchford AP, et al. Temba Glaucoma Study: a Population-based Cross-sectional Survey in Urban South Africa. Ophthalmology. 2003;110(2):376-82. PubMed PMID: 12578784.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Temba glaucoma study: a population-based cross-sectional survey in urban South Africa. AU - Rotchford,Alan P, AU - Kirwan,James F, AU - Muller,Michael A, AU - Johnson,Gordon J, AU - Roux,Paul, PY - 2003/2/13/pubmed PY - 2003/3/4/medline PY - 2003/2/13/entrez SP - 376 EP - 82 JF - Ophthalmology JO - Ophthalmology VL - 110 IS - 2 N2 - OBJECTIVE: To determine the prevalence and features of glaucoma in an urban South African black population. DESIGN: Random sampling cross-sectional population survey. PARTICIPANTS: Black residents of Temba, North West Province, South Africa, age > or =40 years. MAIN OUTCOME MEASURES: Automated visual field testing and detailed, standardized slit-lamp examination were attempted on all subjects. Glaucoma was diagnosed by use of the scheme proposed by the Working Group for Defining Glaucoma of the International Society of Geographical and Epidemiologic Ophthalmology on the basis of evidence of end-organ damage. RESULTS: Of 1120 subjects, 839 (74.9%) were examined. The age- and gender-adjusted prevalence of glaucoma of all types was 5.3% (95% confidence interval [CI], 3.9%-7.1%). Primary open-angle glaucoma (POAG) was the most common glaucoma diagnosis, with an adjusted prevalence of 2.9% (95% CI, 1.9%-4.3%). Secondary glaucoma occurred with an adjusted prevalence of 2.0% (95% CI, 1.2%-3.3%). Exfoliative glaucoma was responsible for 16% of all glaucoma cases. The prevalence of primary angle-closure glaucoma was 0.5% (95% CI, 0.13%-1.2%). Of all subjects with glaucoma, 58% were blind in at least one eye. The prevalence of all types of glaucoma increased with age. Of subjects with POAG, 87% had not been previously diagnosed. CONCLUSIONS: The prevalence of glaucoma in this South African population was higher than that found in white populations, and most cases were undiagnosed and untreated. Glaucoma is a major cause of blindness in this population. SN - 0161-6420 UR - https://www.unboundmedicine.com/medline/citation/12578784/Temba_glaucoma_study:_a_population_based_cross_sectional_survey_in_urban_South_Africa_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(02)01568-3 DB - PRIME DP - Unbound Medicine ER -