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[Studies on chemical constituents of Uvaria macrophylia].
Yao Xue Xue Bao. 2002 Feb; 37(2):124-7.YX

Abstract

AIM

To study the chemical constituents from Uvaria macrophylla Roxb. (Annonaceae).

METHODS

Various chromatography techniques were used to separate and purify the constituents. Their structures were elucidated by UV, IR, MS, 1HNMR, 13CNMR, 1H-1H COSY, HMQC and HMBC spectral analysis.

RESULTS

Seven compounds have been isolated from the CHCl3 extract of the roots of the U. macrophylla. They were identified as macrophyllin (1), onysilin (2), taraxerol (3), 3,5-dimethoxy benzyl benzoic acid ester (4), benzoic acid (5), beta-sitosterol (6) and daucosterol (7).

CONCLUSION

Compound 1 is a new compound. Compounds 2-7 were obtained from this plant for the first time.

Authors+Show Affiliations

Zhang HL
Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Wang S
No affiliation info available
Chen RY
No affiliation info available
Yu DQ
No affiliation info available

MeSH

FlavonoidsMolecular StructureOleanolic AcidPlant RootsPlants, MedicinalSitosterolsUvaria

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

12579957

Citation

Zhang, Hai-ling, et al. "[Studies On Chemical Constituents of Uvaria Macrophylia]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 37, no. 2, 2002, pp. 124-7.
Zhang HL, Wang S, Chen RY, et al. [Studies on chemical constituents of Uvaria macrophylia]. Yao Xue Xue Bao. 2002;37(2):124-7.
Zhang, H. L., Wang, S., Chen, R. Y., & Yu, D. Q. (2002). [Studies on chemical constituents of Uvaria macrophylia]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 37(2), 124-7.
Zhang HL, et al. [Studies On Chemical Constituents of Uvaria Macrophylia]. Yao Xue Xue Bao. 2002;37(2):124-7. PubMed PMID: 12579957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on chemical constituents of Uvaria macrophylia]. AU - Zhang,Hai-ling, AU - Wang,Si, AU - Chen,Ruo-yun, AU - Yu,De-quan, PY - 2003/2/13/pubmed PY - 2004/4/17/medline PY - 2003/2/13/entrez SP - 124 EP - 7 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 37 IS - 2 N2 - AIM: To study the chemical constituents from Uvaria macrophylla Roxb. (Annonaceae). METHODS: Various chromatography techniques were used to separate and purify the constituents. Their structures were elucidated by UV, IR, MS, 1HNMR, 13CNMR, 1H-1H COSY, HMQC and HMBC spectral analysis. RESULTS: Seven compounds have been isolated from the CHCl3 extract of the roots of the U. macrophylla. They were identified as macrophyllin (1), onysilin (2), taraxerol (3), 3,5-dimethoxy benzyl benzoic acid ester (4), benzoic acid (5), beta-sitosterol (6) and daucosterol (7). CONCLUSION: Compound 1 is a new compound. Compounds 2-7 were obtained from this plant for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/12579957/[Studies_on_chemical_constituents_of_Uvaria_macrophylia]_ DB - PRIME DP - Unbound Medicine ER -