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Scurvy: a cutaneous clinical diagnosis.

Abstract

Two cases of scurvy diagnosed following presentation with a purpuric rash are presented. A 44-year-old man developed scurvy as a result of poor dietary intake of vitamin C. This occurred because of a number of factors. including poor dentition, diarrhoea, depression and benzodiazepine/narcotic dependence. A 69-year-old man with acute myeloid leukaemic transformation of myelodysplastic syndrome developed mucositis, nausea, vomiting and diarrhoea as complications of chemotherapy. This led to poor dietary intake and consequently scurvy. Both cases demonstrated specific and diagnostic cutaneous manifestations of scurvy, particularly perifollicular purpura, ecchymoses and coiled corkscrew hairs. The diagnosis was supported by specific diet history. Ascorbic acid tolerance test was used as a simple laboratory method to confirm the clinical diagnosis.

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  • Authors+Show Affiliations

    ,

    Mater Misericordiae Hospitals, Brisbane, Queensland, Australia. rolandtdnguyen@hotmail.com

    ,

    Source

    MeSH

    Adult
    Depression
    Diagnosis, Differential
    Humans
    Leukemia, Myeloid
    Lower Extremity
    Male
    Scurvy
    Skin Diseases

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    12581082

    Citation

    Nguyen, Roland T D., et al. "Scurvy: a Cutaneous Clinical Diagnosis." The Australasian Journal of Dermatology, vol. 44, no. 1, 2003, pp. 48-51.
    Nguyen RT, Cowley DM, Muir JB. Scurvy: a cutaneous clinical diagnosis. Australas J Dermatol. 2003;44(1):48-51.
    Nguyen, R. T., Cowley, D. M., & Muir, J. B. (2003). Scurvy: a cutaneous clinical diagnosis. The Australasian Journal of Dermatology, 44(1), pp. 48-51.
    Nguyen RT, Cowley DM, Muir JB. Scurvy: a Cutaneous Clinical Diagnosis. Australas J Dermatol. 2003;44(1):48-51. PubMed PMID: 12581082.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Scurvy: a cutaneous clinical diagnosis. AU - Nguyen,Roland T D, AU - Cowley,David M, AU - Muir,James B, PY - 2003/2/13/pubmed PY - 2003/3/29/medline PY - 2003/2/13/entrez SP - 48 EP - 51 JF - The Australasian journal of dermatology JO - Australas. J. Dermatol. VL - 44 IS - 1 N2 - Two cases of scurvy diagnosed following presentation with a purpuric rash are presented. A 44-year-old man developed scurvy as a result of poor dietary intake of vitamin C. This occurred because of a number of factors. including poor dentition, diarrhoea, depression and benzodiazepine/narcotic dependence. A 69-year-old man with acute myeloid leukaemic transformation of myelodysplastic syndrome developed mucositis, nausea, vomiting and diarrhoea as complications of chemotherapy. This led to poor dietary intake and consequently scurvy. Both cases demonstrated specific and diagnostic cutaneous manifestations of scurvy, particularly perifollicular purpura, ecchymoses and coiled corkscrew hairs. The diagnosis was supported by specific diet history. Ascorbic acid tolerance test was used as a simple laboratory method to confirm the clinical diagnosis. SN - 0004-8380 UR - https://www.unboundmedicine.com/medline/citation/12581082/Scurvy:_a_cutaneous_clinical_diagnosis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0004-8380&date=2003&volume=44&issue=1&spage=48 DB - PRIME DP - Unbound Medicine ER -